Evidence map›Paper›PMID 37076688›Full record

ArticleEye (London, England)2023

Repeatability of Scheimpflug based corneal tomography parameters in advanced keratoconus with thin corneas.

Himanshu Wadhwa, Akilesh Gokul, Ye Li, Isabella Cheung, Lize Angelo, Charles N J McGhee, Mohammed Ziaei

Open access · greenAbstract read
In one paragraph

Article in Eye (London, England), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Repeatability and agreement of two ocular biometers with single and dual Scheimpflug cameras in keratoconus eyes.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2024
    Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Himanshu WadhwaDepartment of Ophthalmology, University of Auckland, Auckland, New Zealand.ORCID 0000-0002-3287-4453
Akilesh GokulDepartment of Ophthalmology, University of Auckland, Auckland, New Zealand.
Ye LiDepartment of Ophthalmology, University of Auckland, Auckland, New Zealand.ORCID 0000-0002-4585-956X
Isabella CheungDepartment of Ophthalmology, University of Auckland, Auckland, New Zealand.
Lize AngeloDepartment of Ophthalmology, University of Auckland, Auckland, New Zealand.
Charles N J McGheeDepartment of Ophthalmology, University of Auckland, Auckland, New Zealand.ORCID 0000-0001-7048-0706
Mohammed ZiaeiDepartment of Ophthalmology, University of Auckland, Auckland, New Zealand. m.ziaei@auckland.ac.nz.
University of Auckland · NZ

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo determine the repeatability limits of corneal tomography parameters in patients with advanced and moderately thin keratoconic corneas to assist in planning thickness-based procedural interventions.

methodsProspective, single-centre, repeatability study. Three tomography scans using the Pentacam AXL were obtained from patients with keratoconus with thinnest corneal thickness (TCT) ≦400 µm (sub-400 group) and compared to those with TCT = 450-500 µm (450-plus group). Eyes with previous crosslinking, intraocular surgery, or acute corneal hydrops were excluded. Eyes were age and gender-matched. The within-subject standard deviations for flat keratometry (K1), steep keratometry (K2), maximal keratometry (K

resultsThe sub-400 group comprised 114 eyes from 114 participants, and the 450-plus group comprised 114 eyes from 114 participants. In the sub-400 group, TCT was amongst the least repeatable parameters (33.92 µm; ICC 0.96), compared with the 450-plus group (14.32 µm; ICC 0.99, p < 0.01). In the sub-400 group, K1 and K2 of the anterior surface were the most repeatable parameters (r 3.79 and 3.22 respectively; ICC 0.97 and 0.98 respectively) compared with the 450-plus group (r 1.17 and 0.92 respectively; and ICC 0.98 and 0.99 respectively, p < 0.01).

conclusionsThe repeatability of corneal tomography measurements is significantly reduced in sub-400 keratoconic corneas when compared to 450-plus corneas. Repeatability limits should be carefully considered when surgical interventions are planned for such patients.

Indexed as

KeratoconusCorneaCorneal PachymetryCorneal TopographyHumansProspective StudiesReproducibility of ResultsTomography

Identifiers

PMID37076688
PMCPMC10630456
OpenAlexW4366411690

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.