ArticleNature2023
Dedifferentiation maintains melanocyte stem cells in a dynamic niche.
Abstract read
In one paragraph
Article in Nature, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 72 papers.
0numbers the graph read from it
0cells of the map it votes in
72citing papers in PubMed
–field-weighted citation impact
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
72 citing papers in PubMed.
- Dual targeting PD-L1 and 4-1BB to overcome dendritic cell-mediated lenalidomide resistance in follicular lymphoma.Signal transduction and targeted therapy · 2025Trial
- Gasdermin A3 Drives Hair Graying via Ectopic Melanocyte Stem Cell Differentiation and Migration.Stem cell reviews and reports · 2026Article
- Sharp cell type boundaries emerge from coordinated morphogen signaling.Genes & development · 2026Article
- Recent Advances in Genetically Engineered Mouse Models of Melanoma: Insights into Tumor Initiation and Oncogenic Signaling Pathways.International journal of stem cells · 2026Review
- Article
- Moranoline-EnrichedInternational journal of molecular sciences · 2026Article
- Aging of hair follicle stem cells and their niche: mechanisms and regenerative therapeutic strategies.Cell communication and signaling : CCS · 2026Review
- Plerixafor Engages β-Arrestin-Dependent CXCR4 Signaling to Promote Melanogenesis via β-Catenin-MITF Activation.Current issues in molecular biology · 2026Article
- A Review of Randomized Controlled Trials for Vitiligo Therapies Published Between 2013 and 2023.Cureus · 2026Review
- Article
- Protocol to evaluate a lineage marking system in the Drosophila testis.STAR protocols · 2026Article
- Article
- Protective Effects of a New Human Placental Extract Against Hair Graying and Chemotherapy-Induced Peripheral Neuropathy.International journal of molecular sciences · 2026Article
- Aged differentiated cells reverse into native stemness-like state by niche cytokines to sustain lifelong homeostasis and tissue repair.Nature communications · 2026Article
- Aberrant laminin signaling drives melanocyte dedifferentiation and unveils a tractable therapeutic target in vitiligo.Nature communications · 2026Article
- Dissecting the boundary of quiescence and activation of murine melanocyte stem cells in the hair follicle niche.NPJ Regenerative medicine · 2026Review
- Small Nucleolar RNA Snord17 Promotes Self-Renewal of Intestinal Stem Cells through Yy2 mRNA Export and Tead4 Activation.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Natural products and their derivatives as candidate treatments for hair greying: from drug discovery to molecular mechanisms.Chinese medicine · 2026Review
- Plasticity and stringency: rethinking stem cell division modes.Biochemical Society transactions · 2026Review
- A damage-structured PDE model of stem cell hierarchies: The dual role of dedifferentiation in tissue homeostasis and aging.PloS one · 2026Article
12 more citing papers are in PubMed but not listed here.
Corrections and comments
- Commented on by
Authors and funding
13 authors.
Qi SunThe Ronald O. Perelman Department of Dermatology and Department of Cell Biology, New York University Grossman School of Medicine, New York, NY, USA.ORCID http://orcid.org/0000-0002-0495-1407
Wendy LeeThe Ronald O. Perelman Department of Dermatology and Department of Cell Biology, New York University Grossman School of Medicine, New York, NY, USA.
Hai HuThe Ronald O. Perelman Department of Dermatology and Department of Cell Biology, New York University Grossman School of Medicine, New York, NY, USA.
Tatsuya OgawaThe Ronald O. Perelman Department of Dermatology and Department of Cell Biology, New York University Grossman School of Medicine, New York, NY, USA.ORCID http://orcid.org/0000-0003-1124-4572
Sophie De LeonThe Ronald O. Perelman Department of Dermatology and Department of Cell Biology, New York University Grossman School of Medicine, New York, NY, USA.
Ioanna KatehisThe Ronald O. Perelman Department of Dermatology and Department of Cell Biology, New York University Grossman School of Medicine, New York, NY, USA.
Chae Ho LimThe Ronald O. Perelman Department of Dermatology and Department of Cell Biology, New York University Grossman School of Medicine, New York, NY, USA.ORCID http://orcid.org/0000-0002-0787-6748
Makoto TakeoThe Ronald O. Perelman Department of Dermatology and Department of Cell Biology, New York University Grossman School of Medicine, New York, NY, USA.ORCID http://orcid.org/0000-0002-5597-5994
Michael CammerDivision of Advanced Research Technologies, New York University Grossman School of Medicine, New York, NY, USA.ORCID http://orcid.org/0000-0003-4930-1739
M Mark TaketoColon Cancer Program, Kyoto University Hospital-iACT, Kyoto University, Kyoto, Japan.ORCID http://orcid.org/0000-0002-9032-4505
Denise L GayThe Ronald O. Perelman Department of Dermatology and Department of Cell Biology, New York University Grossman School of Medicine, New York, NY, USA.ORCID http://orcid.org/0000-0001-7340-8427
Sarah E MillarBlack Family Stem Cell Institute, Department of Cell, Developmental and Regenerative Biology and Department of Dermatology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.ORCID http://orcid.org/0000-0001-8792-6890
Mayumi ItoThe Ronald O. Perelman Department of Dermatology and Department of Cell Biology, New York University Grossman School of Medicine, New York, NY, USA. mayumi.ito@nyulangone.org.ORCID http://orcid.org/0000-0002-4519-1950
Funding
Vaccine FacilityP30CA016087 · NCI · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI ADRIANA HEGUY · 1985 to 2026
$83.1MProject 3: The Evolving Role of Regional Lymph Nodes in Melanoma ProgressionU54CA263001 · NCI · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI Eva Hernando · 2022 to 2026
$11.6MThe regulation of melanocyte stem cells by Wnt signalingR01AR059768 · NIAMS · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI ITO, MAYUMI · 2011 to 2025
$6.9MConverting wound scar into healing with regenerationR01AR074995 · NIAMS · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI Mayumi Ito · 2020 to 2026
$2.9MMultispectral imaging & analysis of intact tissue sections w/ the Perkin Elmer VectraS10OD021747 · OD · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI LOOMIS, CYNTHIA A · 2016 to 2016
$359kNCI NIH HHS P30 CA016087NCI NIH HHS U54 CA263001NCI NIH HHS U54CA263001-01A1NIAMS NIH HHS R01 AR059768NIAMS NIH HHS R01 AR074995NIH HHS S10 OD021747
Abstract
For unknow reasons, the melanocyte stem cell (McSC) system fails earlier than other adult stem cell populations
Indexed as
Cell DedifferentiationHair FollicleMelanocytesStem Cell NicheStem CellsAgingAnimalsCell LineageCellular MicroenvironmentHair ColorHomeostasisHumansMice
Identifiers
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LicenceCC BY
Read underepoch 390
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.