Evidence map›Paper›PMID 37076579›Full record

ArticleWorld journal of microbiology & biotechnology2023

Gut microbiota regulation and prebiotic properties of polysaccharides from Oudemansiella raphanipes mushroom.

Qi Fang, Yong Lai, Dan Zhang, Hui Lei, Fang Wang, Xiurong Guo, Can Song

Erratum issuedAbstract read
PubMed Publisher
In one paragraph

Article in World journal of microbiology & biotechnology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
3.5field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 23 citations in OpenAlex.

  1. Article
  2. Comparison of Biological Activities ofInternational journal of molecular sciences · 2026
    Article
  3. Article
  4. Review
  5. Review
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. The Role ofMolecules (Basel, Switzerland) · 2025
    Review
  12. Article
  13. Article
  14. Frontiers in nutrition · 2025
    Review
  15. Article
  16. Review
  17. Article
  18. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Qi Fang *School of Pharmacy, Southwest Medical University, Luzhou, Sichuan, 646000, China.
Yong Lai *School of Pharmacy, Southwest Medical University, Luzhou, Sichuan, 646000, China.
Dan ZhangSchool of Pharmacy, Southwest Medical University, Luzhou, Sichuan, 646000, China.
Hui LeiSchool of Pharmacy, Southwest Medical University, Luzhou, Sichuan, 646000, China.
Fang WangSchool of Pharmacy, Southwest Medical University, Luzhou, Sichuan, 646000, China.
Xiurong GuoSchool of Pharmacy, Southwest Medical University, Luzhou, Sichuan, 646000, China.
Can SongSchool of Pharmacy, Southwest Medical University, Luzhou, Sichuan, 646000, China. cansong@swmu.edu.cn.
Southwest Medical University · CN

Funding

the Applied Basic Research Cooperation Project of Luzhou Government-Southwest Medical University 2020LZXNYDJ28the Scientific Research Foundation for Talent Introduction of Southwest Medical University 0903-00040031
6 · The paper itself

Abstract

Oudemansiella raphanipes is a type of fungus used as both medicine and food. Fungal polysaccharides have demonstrated various bioactivities, involving the adjust and control of gut microbiota, but no such studies on O. raphanipes polysaccharides (OrPs) have been reported. It is by extracting and purifying that OrPs was obtained from O. raphanipes crude polysaccharide and study their effects in mice. The sample contents of total sugar was 97.26%, and the monosaccharide content comprised mannose, rhamnose, glucose, and xylose in a molar ratio of 35.2:2.8:21.2:40.8. The effects of OrPs on body weight (BW), gut microbiota, fecal short-chain fatty acids (SCFAs), and the correlation between fecal SCFAs and gut microbes, in mice were investigated. The results of the experiment found that OrPs significantly (P < 0.01) inhibited the increase in BW, altered the constitution of the gut microbiota, and significantly (P < 0.05) enhanced the content of fecal SCFAs in mice. Moreover, among the top ten bacteria in terms of relative abundance, the Lachnospiraceae and Lachnospiraceae NK4A136 groups were positively associated with the increased production of SCFAs. Other bacteria, such as Atopobiaceae and Bifidobacterium of Actinobacteriota, and Faecalibaculum, Dubosiella, and Clostridium sensu stricto 5 of Firmicutes, were also positively associated with higher content of fecal SCFAs. The results of the experiment suggest that OrPs have a potential prebiotic effect on gut microbiota and may prevent BW gain. Furthermore, the major producers of SCFAs were Firmicutes and Actinobacteriota.

Indexed as

AgaricalesGastrointestinal MicrobiomeAnimalsBacteriaFatty Acids, VolatileMicePolysaccharidesPrebioticsFatty Acids, VolatilePolysaccharidesPrebioticsGut microbiotaOudemansiella raphanipesPolysaccharidesPrebioticSCFAs

Identifiers

PMID37076579
OpenAlexW4366528423

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.