ArticleScientific reports2023
Fronto-central resting-state 15-29 Hz transient beta events change with therapeutic transcranial magnetic stimulation for posttraumatic stress disorder and major depressive disorder.
Article in Scientific reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it, 25 citations in OpenAlex.
- Pooled it
- Transient frontal spectral events from EEG predict antidepressant response to sertraline in depression.Journal of psychiatric research · 2026Trial
- Dysfunctional oscillatory bursting patterns linked to working memory in adolescents with attention deficit hyperactivity disorder.Cognitive, affective & behavioral neuroscience · 2026Article
- The Association between Oscillatory Burst Features and Human Working Memory Accuracy.Journal of cognitive neuroscience · 2026Article
- Stanford neuromodulation therapy for treatment-resistant depression: a randomized controlled trial confirming efficacy, and an EEG study providing insight into mechanism of action and a potentially predictive biomarker of efficacy.World psychiatry : official journal of the World Psychiatric Association (WPA) · 2026Article
- Multiband EEG signatures decoded using machine learning for predicting rTMS treatment response in MDD.Journal of affective disorders · 2025Article
- Article
- High-power transient 12-30 Hz beta event features as early biomarkers of Alzheimer's disease conversion: An MEG study.Imaging neuroscience (Cambridge, Mass.) · 2025Article
- Transcranial Magnetic Stimulation for Posttraumatic Stress Disorder and Generalized Anxiety Disorder.Current topics in behavioral neurosciences · 2025Review
- The Effects of Repetitive Transcranial Magnetic Stimulation on Post-Traumatic Stress Disorder and Parameter Discussion: A Meta-Analysis Based on Randomized Controlled Trials.Neuropsychiatric disease and treatment · 2025Review
- Advances in Repetitive Transcranial Magnetic Stimulation for the Treatment of Post-traumatic Stress Disorder.Alpha psychiatry · 2024Review
- Frontoparietal beta event characteristics are associated with early life stress and psychiatric symptoms in adults.Brain and cognition · 2024Article
- Bursting with Potential: How Sensorimotor Beta Bursts Develop from Infancy to Adulthood.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2023Article
- Pre-treatment frontal beta events are associated with executive dysfunction improvement after repetitive transcranial magnetic stimulation for depression: A preliminary report.Journal of psychiatric research · 2023Article
- A Study of Brain Function Characteristics of Service Members at High Risk for Accidents in the Military.Brain sciences · 2023Article
- Examining the neural mechanisms of rTMS: a naturalistic pilot study of acute and serial effects in pharmacoresistant depression.Frontiers in neural circuits · 2023Article
Corrections and comments
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Authors and funding
9 authors at 2 institutions in 1 country.
Funding
Abstract
Repetitive transcranial magnetic stimulation (rTMS) is an established treatment for major depressive disorder (MDD) and shows promise for posttraumatic stress disorder (PTSD), yet effectiveness varies. Electroencephalography (EEG) can identify rTMS-associated brain changes. EEG oscillations are often examined using averaging approaches that mask finer time-scale dynamics. Recent advances show some brain oscillations emerge as transient increases in power, a phenomenon termed "Spectral Events," and that event characteristics correspond with cognitive functions. We applied Spectral Event analyses to identify potential EEG biomarkers of effective rTMS treatment. Resting 8-electrode EEG was collected from 23 patients with MDD and PTSD before and after 5 Hz rTMS targeting the left dorsolateral prefrontal cortex. Using an open-source toolbox ( https://github.com/jonescompneurolab/SpectralEvents ), we quantified event features and tested for treatment associated changes. Spectral Events in delta/theta (1-6 Hz), alpha (7-14 Hz), and beta (15-29 Hz) bands occurred in all patients. rTMS-induced improvement in comorbid MDD PTSD were associated with pre- to post-treatment changes in fronto-central electrode beta event features, including frontal beta event frequency spans and durations, and central beta event maxima power. Furthermore, frontal pre-treatment beta event duration correlated negatively with MDD symptom improvement. Beta events may provide new biomarkers of clinical response and advance the understanding of rTMS.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.