ArticleEnvironment international2023
Maternal urinary bisphenols and phthalates in relation to estimated fetal weight across mid to late pregnancy.
Article in Environment international, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 22 citations in OpenAlex.
- Article
- Exposure to bisphenols and phthalates and arterial stiffness in women of reproductive age: a New York City cohort analysis.Environment international · 2026Article
- Association of umbilical cord blood phthalate levels with neonatal growth parameters in term pregnancies.BMC pediatrics · 2026Article
- Associations of prenatal exposure to bisphenols and phthalates with the fetoplacental ratio in the New York University Children's Health and Environment Study (NYU CHES).Ecotoxicology and environmental safety · 2026Article
- Oxidative stress and fetal weight: observational findings from a pregnancy cohort in New York City.Journal of perinatology : official journal of the California Perinatal Association · 2026Observational
- Placental angiogenic biomarkers in relation to prenatal bisphenol and phthalate exposure.Placenta · 2026Article
- Prenatal exposure to phthalates and alternative plasticizers and emotional and behavioral outcomes in early childhood in the Environmental influences on Child Health outcomes (ECHO) cohort.Environment international · 2025Article
- Development and child health in a world of synthetic chemicals.Pediatric research · 2025Review
- Prenatal phthalate exposure and anogenital distance in infants at 12 months.Environment international · 2025Article
- Environmental Phenols and Growth in Infancy: The Infant Feeding and Early Development Study.The Journal of clinical endocrinology and metabolism · 2024Article
- Evaluating associations of bisphenol and phthalate exposure with time to pregnancy and subfecundity in a New York City pregnancy cohort.Environmental pollution (Barking, Essex : 1987) · 2024Article
- Sex-Specific Associations between Prenatal Exposure to Bisphenols and Phthalates and Infant Epigenetic Age Acceleration.Epigenomes · 2024Article
- Prenatal exposure to environmental phenols and fetal growth across pregnancy in the LIFECODES fetal growth study.Environment international · 2024Article
- Maternal Prenatal Depressive Symptoms and Fetal Growth During the Critical Rapid Growth Stage.JAMA network open · 2023Article
Corrections and comments
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Authors and funding
14 authors at 3 institutions in 1 country.
Funding
Abstract
backgroundBisphenols and phthalates are high production volume chemicals used as additives in a variety of plastic consumer products leading to near ubiquitous human exposure. These chemicals have established endocrine disrupting properties and have been linked to a range of adverse reproductive and developmental outcomes. Here, we investigated exposure in relation to fetal growth.
methodsParticipants included 855 mother-fetal pairs enrolled in the population-based New York University Children's Health and Environment Study (NYU CHES). Bisphenols and phthalates were measured in maternal urine collected repeatedly during pregnancy. Analyses included 15 phthalate metabolites and 2 bisphenols that were detected in 50 % of participants or more. Fetal biometry data were extracted from electronic ultrasonography records and estimated fetal weight (EFW) was predicted for all fetuses at 20, 30, and 36 weeks gestation. We used quantile regression adjusted for covariates to model exposure-outcome relations across percentiles of fetal weight at each gestational timepoint. We examined sex differences using stratified models.
resultsFew statistically significant associations were observed across chemicals, gestational time periods, percentiles, and sexes. However, within gestational timepoints, we found that among females, the molar sums of the phthalates DiNP and DnOP were generally associated with decreases in EFW among smaller babies and increases in EFW among larger babies. Among males, the opposite trend was observed. However, confidence intervals were generally wide at the tails of the distribution.
conclusionIn this sample, exposure to bisphenols and phthalates was associated with small sex-specific shifts in fetal growth; however, few associations were observed at the median of fetal weight and confidence intervals in the tails were wide. Findings were strongest for DiNP and DnOP, which are increasingly used as replacements for DEHP, supporting the need for future research on these contaminants.
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