SynthesisSao Paulo medical journal = Revista paulista de medicina2023
Diagnostic criteria and outcome measures in randomized clinical trials on carpal tunnel syndrome: a systematic review.
Synthesis in Sao Paulo medical journal = Revista paulista de medicina, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07249177 (Validity and Reliability of the Upper Extremity Functional Index in Patients With Carpal Tunnel Syndrome), which is not on this map. Cited by 2 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Validity and Reliability of the Upper Extremity Functional Index in Patients With Carpal Tunnel Syndrome
Who cites it
2 citing papers in PubMed, 1 synthesis or guideline pooled it.
- "Outcome measures in Iranian studies of carpal tunnel syndrome surgery: a systematic review".BMC surgery · 2026Pooled it
- How Well Does ChatGPT-4o Reason? Expert Evaluation of Diagnostic and Therapeutic Performance in Hand Surgery.Journal of clinical medicine · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe diagnostic criteria for carpal tunnel syndrome (CTS) lack uniformity. Moreover, because CTS is a syndrome, there is no consensus as to which signs, symptoms, clinical and complementary tests are more reproducible and accurate for use in clinical research. This heterogeneity is reflected in clinical practice. Thus, establishing effective and comparable care protocols is difficult.
objectiveTo identify the diagnostic criteria and outcome measures used in randomized clinical trials (RCTs) on CTS. DESING AND
settingSystematic review of randomized clinical trials carried out at the Federal University of São Paulo, São Paulo, Brazil.
methodsWe searched the Cochrane Library, PubMed, and Embase databases for RCTs with surgical intervention for CTS published between 2006 and 2019. Two investigators independently extracted relevant data on diagnosis and outcomes used in these studies.
resultsWe identified 582 studies and 35 were systematically reviewed. The symptoms, paresthesia in the median nerve territory, nocturnal paresthesia, and special tests were the most widely used clinical diagnostic criteria. The most frequently assessed outcomes were symptoms of paresthesia in the median nerve territory and nocturnal paresthesia.
conclusionThe diagnostic criteria and outcome measures used in RCTs about CTS are heterogeneous, rendering comparison of studies difficult. Most studies use unstructured clinical criteria associated with ENMG for diagnosis. The Boston Questionnaire is the most frequently used main instrument to measure outcomes. REGISTRATION: PROSPERO (CRD42020150965- https://www.crd.york.ac.uk/prospero/display_record.php?RecordID=150965).
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.