Evidence map›Paper›PMID 37075336›Full record

ReviewRevista do Instituto de Medicina Tropical de Sao Paulo2023

Acid-fast bacteria as causative agents of skin and soft tissue infections: case presentations and literature review.

Anastasia Spiliopoulou, Georgia Kyriakou, Sophia Georgiou, Alexandra Lekkou, Lydia Leonidou, Maria Militsopoulou, Eleni Papadogeorgaki, Myrto Christofidou, Fevronia Kolonitsiou, Fotini Paliogianni

Open access · diamondAbstract readReview
In one paragraph

Review in Revista do Instituto de Medicina Tropical de Sao Paulo, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

  1. Primary cutaneous nocardiosis caused byFrontiers in medicine · 2026
    Article
  2. Journal of family medicine and primary care · 2025
    Article
  3. Article
  4. Acute Primary Cutaneous Nocardiosis.The American journal of tropical medicine and hygiene · 2024
    Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Anastasia SpiliopoulouUniversity General Hospital of Patras, Department of Microbiology, Patras, Greece.ORCID http://orcid.org/0000-0001-9125-8098
Georgia KyriakouUniversity General Hospital of Patras, Department of Dermatology, Patras, Greece.ORCID http://orcid.org/0000-0002-3907-5654
Sophia GeorgiouUniversity General Hospital of Patras, Department of Dermatology, Patras, Greece.ORCID http://orcid.org/0000-0003-4079-8101
Alexandra LekkouUniversity General Hospital of Patras, Department of Infectious Diseases, Patras, Greece.
Lydia LeonidouUniversity General Hospital of Patras, Department of Infectious Diseases, Patras, Greece.
Maria MilitsopoulouUniversity General Hospital of Patras, Department of Microbiology, Patras, Greece.
Eleni PapadogeorgakiDiagnostic and Therapeutic Center of Athens Hygeia S.A., Athens, Greece.
Myrto ChristofidouUniversity General Hospital of Patras, Department of Microbiology, Patras, Greece.
Fevronia KolonitsiouUniversity General Hospital of Patras, Department of Microbiology, Patras, Greece.ORCID http://orcid.org/0000-0002-4348-6077
Fotini PaliogianniUniversity General Hospital of Patras, Department of Microbiology, Patras, Greece.ORCID http://orcid.org/0000-0001-5112-1724
General University Hospital of Patras · GRHygeia Hospital · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Acid-fast bacteria can be implicated in skin and soft tissue infections. Diagnostic identification can be challenging or not feasible by routine laboratory techniques, especially if there is no access to the Matrix Assisted Laser Desorption Ionization Time of Flight Mass Spectrometry (MALDI-TOF MS) technology. Here, we present two cases of skin and soft tissue infections caused by two different acid-fast bacteria, Nocardia brasiliensis and Mycobacterium marinum. They both grew on Löwenstein-Jensen medium, Sabouraud agar medium and blood agar medium. Both bacteria appeared acid-fast by Ziehl-Neelsen stain and Gram-positive by Gram stain. The identification was performed by MALDI-TOF MS and gene analysis. N. brasiliensis and nontuberculous mycobacterium M. marinum represent rare pathogens that cause severe skin and soft tissue infections. Failure to identify the causative agent and subsequent inappropriate or inadequate treatment may lead to severe complications or even disseminated disease, especially in immunocompromised individuals.

Indexed as

Mycobacterium marinumSoft Tissue InfectionsAgarBacteriaCulture MediaHumansSpectrometry, Mass, Matrix-Assisted Laser Desorption-IonizationAgarCulture Media

Identifiers

PMID37075336
PMCPMC10115452
OpenAlexW4365803927

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.