Evidence map›Paper›PMID 37074780›Full record

ArticleJMIR formative research2023

Patient Feedback on a Mobile Medication Adherence App for Buprenorphine and Naloxone: Closed and Open-Ended Survey on Feasibility and Acceptability.

Crystal L Smith, Abigail Keever, Theresa Bowden, Katie Olson, Nicole Rodin, Michael G McDonell, John M Roll, Gillian Smoody, Jeff LeBrun, Andre Qc Miguel and 1 more

Open access · goldAbstract read
In one paragraph

Article in JMIR formative research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 3 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Crystal L SmithDepartment of Community and Behavioral Health, Elson S Floyd College of Medicine, Washington State University, Spokane, WA, United States.ORCID https://orcid.org/0000-0002-5095-2822
Abigail KeeverDepartment of Community and Behavioral Health, Elson S Floyd College of Medicine, Washington State University, Spokane, WA, United States.ORCID https://orcid.org/0000-0001-5147-0510
Theresa BowdenAnalytics and PsychoPharmacology Laboratory, Washington State University, Spokane, WA, United States.ORCID https://orcid.org/0000-0002-4659-8824
Katie OlsonIdeal Option, Spokane, WA, United States.ORCID https://orcid.org/0000-0001-6622-9922
Nicole RodinAnalytics and PsychoPharmacology Laboratory, Washington State University, Spokane, WA, United States.ORCID https://orcid.org/0000-0001-9522-3677
Michael G McDonellDepartment of Community and Behavioral Health, Elson S Floyd College of Medicine, Washington State University, Spokane, WA, United States.ORCID https://orcid.org/0000-0002-8372-6469
John M RollDepartment of Community and Behavioral Health, Elson S Floyd College of Medicine, Washington State University, Spokane, WA, United States.ORCID https://orcid.org/0000-0002-7677-9108
Gillian SmoodyAnalytics and PsychoPharmacology Laboratory, Washington State University, Spokane, WA, United States.ORCID https://orcid.org/0000-0002-2383-3190
Jeff LeBrunOptimize Health, Seattle, WA, United States.ORCID https://orcid.org/0000-0002-8537-1630
Andre Qc MiguelDepartment of Community and Behavioral Health, Elson S Floyd College of Medicine, Washington State University, Spokane, WA, United States.ORCID https://orcid.org/0000-0003-3203-3889
Sterling M McPhersonDepartment of Community and Behavioral Health, Elson S Floyd College of Medicine, Washington State University, Spokane, WA, United States.ORCID https://orcid.org/0000-0003-2551-4772
Washington State University Spokane · USiDEAL Technology (United States) · US

Funding

Connected Pharmacy Platform to Improve Adherence to Buprenorphine-Naloxone Prescription Treatment of Opioid Use DisorderR44DA049629 · NIDA · OPTIMIZE SYSTEMS INC · PI LEBRUN, JEFFREY, MCPHERSON, STERLING M · 2019 to 2019
$235k
NIDA NIH HHS R44 DA049629
6 · The paper itself

Abstract

backgroundOpioid use disorders impact the health and well-being of millions of Americans. Buprenorphine and naloxone (BUP and NAL) can reduce opioid overdose deaths, decrease misuse, and improve quality of life. Unfortunately, poor medication adherence is a primary barrier to the long-term efficacy of BUP and NAL.

objectiveWe aimed to examine patient feedback on current and potential features of a Bluetooth-enabled pill bottle cap and associated mobile app for patients prescribed BUP and NAL for an opioid use disorder, and to solicit recommendations for improvement to effectively and appropriately tailor the technology for people in treatment for opioid use disorder.

methodsA convenience sample of patients at an opioid use disorder outpatient clinic were asked about medication adherence, opioid cravings, experience with technology, motivation for treatment, and their existent support system through a brief e-survey. Patients also provided detailed feedback on current features and features being considered for inclusion in a technology designed to increase medication adherence (eg, inclusion of a personal motivational factor, craving and stress tracking, incentives, and web-based coaching). Participants were asked to provide suggestions for improvement and considerations specifically applicable to people in treatment for opioid use disorder with BUP and NAL.

resultsTwenty people with an opioid use disorder who were prescribed BUP and NAL participated (mean age 34, SD 8.67 years; 65% female; 80% White). Participants selected the most useful, second-most useful, and least useful features presented; 42.1% of them indicated that motivational reminders would be most useful, followed by craving and stress tracking (26.3%) and web-based support forums (21.1%). Every participant indicated that they had at least 1 strong motivating factor for staying in treatment, and half (n=10) indicated children as that factor. All participants indicated that they had, at some point in their lives, the most extreme craving a person could have; however, 42.1% indicated that they had no cravings in the last month. Most respondents (73.7%) stated that tracking cravings would be helpful. Most respondents (84.2%) also indicated that they believed reinforcers or prizes would help them achieve their treatment goals. Additionally, 94.7% of respondents approved of adherence tracking to accommodate this feature using smart packaging, and 78.9% of them approved of selfie videos of them taking their medication.

conclusionsEngaging patients taking treatment for opioid use disorder with BUP and NAL allowed us to identify preferences and considerations that are unique to this treatment area. As the technology developer of the pill cap and associated mobile app is able to take into consideration or integrate these preferences and suggestions, the smart cap and associated mobile app will become tailored to this population and more useful for them, which may encourage patient use of the smart cap and associated mobile app.

Indexed as

buprenorphinecliniccoachingincentivemedicationmedication adherencemedication-assisted treatmentmedications for opioid use disordermobile phonemobile technologynaloxoneopioidopioid agonist therapyopioidsopioid useopioid use disorderquality of liferemotestresstechnologytooltrackingwell-being

Identifiers

PMID37074780
PMCPMC10157459
OpenAlexW4320807295

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.