Evidence map›Paper›PMID 37074599›Full record

ArticleOdontology2024

Effect of ELVAX polymer subgingival implants with echistatin on extracted and reimplanted rats' teeth.

Bethânia Camargo Pinheiro, Tiago Novaes Pinheiro, Milena Gomes Melo Leite, Roberto Brandão Garcia, Norberti Bernardineli, Flávio Duarte Faria, Luciano Tavares Angelo Cintra, Clovis Monteiro Bramante

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In one paragraph

Article in Odontology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 92% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Bethânia Camargo PinheiroDepartment of Dentistry, Endodontics, and Dental Materials, Bauru School of Dentistry, University of São Paulo, Bauru, SP, Brazil.
Tiago Novaes PinheiroDepartment of Oral Pathology and Oral Medicine, Dental School of Amazonas State University, Manaus, AM, Brazil.
Milena Gomes Melo LeiteDepartment of Oral Pathology and Oral Medicine, Dental School of Amazonas State University, Manaus, AM, Brazil.
Roberto Brandão GarciaDepartment of Dentistry, Endodontics, and Dental Materials, Bauru School of Dentistry, University of São Paulo, Bauru, SP, Brazil.
Norberti BernardineliDepartment of Dentistry, Endodontics, and Dental Materials, Bauru School of Dentistry, University of São Paulo, Bauru, SP, Brazil.
Flávio Duarte FariaDepartment of Preventive and Restorative Dentistry, School of Dentistry, São Paulo State University (Unesp), José Bonifácio, 1193, Vila Mendonça, Araçatuba, SP, CEP 16015-050, Brazil.
Luciano Tavares Angelo CintraDepartment of Preventive and Restorative Dentistry, School of Dentistry, São Paulo State University (Unesp), José Bonifácio, 1193, Vila Mendonça, Araçatuba, SP, CEP 16015-050, Brazil. luciano.cintra@unesp.br.ORCID http://orcid.org/0000-0003-2348-7846
Clovis Monteiro BramanteDepartment of Dentistry, Endodontics, and Dental Materials, Bauru School of Dentistry, University of São Paulo, Bauru, SP, Brazil.
Universidade de São Paulo · BRUniversidade do Estado do Amazonas · BRUniversidade Estadual Paulista (Unesp) · BR

Funding

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior Financial code 001
6 · The paper itself

Abstract

To investigate the effect of ELVAX polymer subgingival implants incorporated with echistatin peptide on incisor reimplanted tooth in rats. Forty-two male Wistars rats were divided into two groups: echistatin-treated rats (E) and control rats (C). The animals had their right maxillary incisors extracted and treated according to the International Association of Dental Traumatology replantation protocol. The extra-alveolar dry period was 30 and 60 min, and the post-surgical experimental periods were 15, 60, and 90 days. The samples were stained with H&E and analyzed for the presence of an inflammatory response, incidence of resorptions, and dental ankylosis. Results were statistically analyzed (p < 0.05). The presence of inflammatory resorption was significantly higher in group C at 30 and 60 min extra-alveolar time, in the 15-day postoperative period as compared with the E group (p < 0.05). Dental ankylosis was significantly more prevalent in group E in 30 min extra-alveolar time and 15 days postoperative period (p < 0.05). However, in 60 min extra-alveolar time and 60 days postoperative period, dental ankylosis was more prevalent in C group (p < 0.05). The use of ELVAX subgingival implants with echistatin demonstrated therapeutic potential in preventing the experimental resorption process after replantation of maxillary incisors in rats.

Indexed as

Dental ImplantsRoot ResorptionTooth AnkylosisAnimalsIntercellular Signaling Peptides and ProteinsMalePolymersPolyvinylsRatsRats, WistarTooth ReplantationDental Implantsechistatinethylenevinylacetate copolymerIntercellular Signaling Peptides and ProteinsPolymersPolyvinylsEchistatinRoot resorptionTooth avulsion

Identifiers

PMID37074599
OpenAlexW4366351751

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.