ArticleBrazilian journal of microbiology : [publication of the Brazilian Society for Microbiology]2023
Molecular detection of Burkholderia mallei in different geographic regions of Brazil.
Article in Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology], 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed, 9 citations in OpenAlex.
- Construction of an RPA-CRISPR visualization system for rapid detection of Burkholderia mallei.BMC microbiology · 2026Article
- Detection ofPathogens (Basel, Switzerland) · 2025Article
- Glanders: An ancient and emergent disease with no vaccine or treatment on site.PLoS neglected tropical diseases · 2025Review
- Clinical and Molecular Characterization of Human Burkholderia mallei Infection, Brazil.Emerging infectious diseases · 2024Article
- Assessment of the Virulence of theMicroorganisms · 2023Article
- Glanders Diagnosis in an Asymptomatic Mare from Brazil: Insights from Serology, Microbiological Culture, Mass Spectrometry, and Genome Sequencing.Pathogens (Basel, Switzerland) · 2023Article
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Authors and funding
13 authors at 6 institutions in 1 country.
Funding
Abstract
Glanders is a contagious disease of equids caused by the Gram-negative bacterium Burkholderia mallei. In Brazil, the disease is considered to be reemerging and has been expanding, with records of equids with positive serology in most of the federative units. However, there are few reports describing the genotypic detection of the agent. This study demonstrated the detection of B. mallei by species-specific PCR directly from tissues or from bacterial cultures, followed by amplicon sequencing in equids (equines, mules, and asinines) with positive serology for glanders in all five geographic regions of Brazil. The molecular evidence of B. mallei infection in serologically positive equids in this study expands the possibility of strain isolation and the conduction of epidemiological characterizations based on molecular information. The microbiological detection of B. mallei in cultures from nasal and palate swabs, even in equids without clinical manifestations, raises the possibility of environmental elimination of the agent.
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Registered trials
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