Evidence map›Paper›PMID 37074528›Full record

ReviewCurrent HIV/AIDS reports2023

Reporting Individual-Level Research Results from Neurocognitive and Psychological Research in People Living with HIV: Lessons from Dementia Research.

Holly L Peay, Stuart Rennie, Gail E Henderson

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current HIV/AIDS reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Holly L PeayRTI International, 3040 E Cornwallis Rd., Research Triangle Park, Durham, NC, 27709, USA. hpeay@rti.org.ORCID 0000-0002-3053-7453
Stuart RennieCenter for Bioethics, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Gail E HendersonSocial Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.

Funding

Integrating Decision Making Studies into HIV Cure Trials: A real-time longitudinal assessmentR01AI127024 · NIAID · UNIV OF NORTH CAROLINA CHAPEL HILL · PI HENDERSON, GAIL E · 2016 to 2019
$2.2M
Decision Support for Early-Phase HIV Remission TrialsR34MH123328 · NIMH · UNIV OF NORTH CAROLINA CHAPEL HILL · PI HENDERSON, GAIL E, PEAY, HOLLY LANDRUM · 2021 to 2022
$760k
NIAID NIH HHS R01 AI127024NIMH NIH HHS R34 MH123328
6 · The paper itself

Abstract

purpose of reviewThere are growing expectations for the return of individual-level research results (RoR), which promotes autonomy and potential clinical and personal benefits. There are ethical and practical challenges, however, that may be exacerbated in research that assesses neurocognitive and psychological outcomes, including HIV-associated neurocognitive disorder (HAND). This paper reviews central concepts for RoR and recent empirical and conceptual articles from Alzheimer's disorder (AD) as a model for HIV. RECENT

findingsData from AD studies indicate high participant interest and low risk of harm from RoR, though additional research is needed. Investigators report a range of benefits, potential risks, and feasibility concerns. Standardized, evidence-based approaches are needed for RoR. For HIV research, we recommend a default position of offering RoR for cognitive and psychological outcomes. Investigators should justify decisions not to return results after assessing the potential value and feasibility of RoR. Longitudinal research is needed for feasible and evidence-based best practices.

Indexed as

DementiaHIV InfectionsHumansNeurocognitive DisordersEthicsHANDHIVNeurocognitiveResearchReturn of results

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.