Evidence map›Paper›PMID 37074092›Full record

ReviewJournal of clinical research in pediatric endocrinology2024

Seminoma in 46, XY Gonadal Dysgenesis: Rare Presentation and Review of the Literature

Maamoun Adra, Hayato Nakanishi, Eleni Papachristodoulou, Evangelia Karaoli, Petroula Gerasimou, Antri Miltiadous, Katerina Nicolaou, Loizos Loizou, Nicos Skordis

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PubMed Full text at PMC Publisher
In one paragraph

Review in Journal of clinical research in pediatric endocrinology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 87% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 0 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Maamoun AdraSt George’s University of London Medical School, London, UKORCID 0000-0003-4283-7629
Hayato NakanishiSt George’s University of London Medical School, London, UKORCID 0000-0002-2883-722X
Eleni PapachristodoulouMakarios Hospital, Clinic of Paediatric Oncology, Nicosia, CyprusORCID 0000-0002-6903-1783
Evangelia KaraoliMakarios Hospital, Clinic of Paediatric Oncology, Nicosia, CyprusORCID 0000-0001-6206-0947
Petroula GerasimouKaraiskakio Foundation, Molecular Hematology-Oncology, Nicosia, CyprusORCID 0000-0001-8970-9056
Antri MiltiadousKaraiskakio Foundation, Molecular Hematology-Oncology, Nicosia, CyprusORCID 0000-0002-5588-4021
Katerina NicolaouKaraiskakio Foundation, Molecular Hematology-Oncology, Nicosia, CyprusORCID 0000-0001-7996-0183
Loizos LoizouMakarios Hospital, Clinic of Paediatric Oncology, Nicosia, CyprusORCID 0000-0003-1781-5030
Nicos SkordisSt George’s University of London Medical School, London, UKORCID 0000-0002-0338-8317
University of Nicosia · CYArchbishop Makarios III Hospital · CYSt George's, University of London · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Swyer syndrome is a rare congenital condition that serves as a risk factor for developing germ cell tumors. The condition belongs to the group of 46, XY disorders of sexual development, is characterized by complete gonadal dysgenesis (CGD) and is mostly manifested as delayed puberty and primary amenorrhea during adolescence. Individuals with Swyer syndrome are known to be phenotypically female with normal internal and external female genitalia at birth. 46, XY GD involves a high risk of gonadoblastoma development with malignant potential such that the onset is greatest at or after the event of puberty. This report of a 12-year-old phenotypic female with 46, XY GD, who developed an advanced metastatic seminoma, highlights the rarity of the development of a seminoma in the context of 46, XY CGD.

Indexed as

Gonadal Dysgenesis, 46,XYSeminomaChildFemaleHumansMaleTesticular Neoplasms46, XYgonadal dysgenesisSeminomaSwyer syndrome

Identifiers

PMID37074092
PMCPMC11629731
OpenAlexW4366351012

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.