Evidence map›Paper›PMID 37073981›Full record

ArticleJournal of neurophysiology2023

Spike timing-dependent plasticity alters electrosensory neuron synaptic strength in vitro but does not consistently predict changes in sensory tuning in vivo.

Adalee J Lube, Xiaofeng Ma, Bruce A Carlson

Abstract read
In one paragraph

Article in Journal of neurophysiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Adalee J LubeDepartment of Biology, Washington University in St. Louis, St. Louis, Missouri, United States.ORCID 0000-0001-6969-5478
Xiaofeng MaDepartment of Biology, Washington University in St. Louis, St. Louis, Missouri, United States.
Bruce A CarlsonDepartment of Biology, Washington University in St. Louis, St. Louis, Missouri, United States.ORCID 0000-0002-2151-0443

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

How do sensory systems optimize detection of behaviorally relevant stimuli when the sensory environment is constantly changing? We addressed the role of spike timing-dependent plasticity (STDP) in driving changes in synaptic strength in a sensory pathway and whether those changes in synaptic strength could alter sensory tuning. It is challenging to precisely control temporal patterns of synaptic activity in vivo and replicate those patterns in vitro in behaviorally relevant ways. This makes it difficult to make connections between STDP-induced changes in synaptic physiology and plasticity in sensory systems. Using the mormyrid species

Indexed as

Electric FishNeuronsAction PotentialsAnimalsCentral Nervous SystemInterneuronsNeuronal PlasticitySynapsesHebbian plasticitysensory processingsynaptic plasticitytemporal codingweakly electric fish

Identifiers

PMID37073981
PMCPMC10151048

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.