Evidence map›Paper›PMID 37073967›Full record

ArticleJournal of neurophysiology2023

Series resistance errors in whole cell voltage clamp measured directly with dual patch-clamp recordings: not as bad as you think.

Michael Gray, Joseph M Santin

Open access · greenAbstract read
In one paragraph

Article in Journal of neurophysiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.3field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Michael GrayDivision of Biological Sciences, University of Missouri, Columbia, Missouri, United States.
Joseph M SantinDivision of Biological Sciences, University of Missouri, Columbia, Missouri, United States.ORCID 0000-0003-1308-623X
University of Missouri · US

Funding

Homeostatic plasticity mechanisms regulate behavior in vivoR01NS114514 · NINDS · UNIVERSITY OF NORTH CAROLINA GREENSBORO · PI Joseph M Santin · 2021 to 2026
$1.5M
NIH HHS R01NS114514NINDS NIH HHS R01 NS114514
6 · The paper itself

Abstract

Whole cell patch clamp has provided much insight into the function of voltage-gated ion channels in central neurons. However, voltage errors caused by the resistance of the recording electrode [series resistance (

Indexed as

Ion ChannelsMotor NeuronsElectrodesMembrane PotentialsIon ChannelsK+ currentspatch clampseries resistancevoltage clampvoltage error

Identifiers

PMID37073967
PMCPMC10190937
OpenAlexW4366351816

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.