Evidence map›Paper›PMID 37073568›Full record

ArticleThe EMBO journal2023

A tale of two Hippo pathway modules.

Han Han, Wenqi Wang

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The EMBO journal, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. A tale of two Hippo pathway modules.The EMBO journal · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Han HanDepartment of Developmental and Cell Biology, University of California Irvine, Irvine, CA, USA.ORCID 0000-0003-2222-5270
Wenqi WangDepartment of Developmental and Cell Biology, University of California Irvine, Irvine, CA, USA.ORCID 0000-0003-4053-5088

Funding

Regulation and function of the Hippo pathway in growth controlR01GM126048 · NIGMS · UNIVERSITY OF CALIFORNIA-IRVINE · PI Wenqi Wang · 2018 to 2026
$3.0M
Interplay of heavy metal homeostasis and cell growth-related signaling networksR01GM143233 · NIGMS · UNIVERSITY OF CALIFORNIA-IRVINE · PI WANG, WENQI, WARRIOR, RAHUL · 2022 to 2025
$1.2M
NIGMS NIH HHS R01 GM126048NIGMS NIH HHS R01 GM143233
6 · The paper itself

Abstract

The Hippo pathway is an evolutionarily conserved pathway with crucial roles in development, organ size control, tissue homeostasis and cancer. Over two decades of research have elucidated the core Hippo pathway kinase cascade, but its precise organization has not been fully understood. In this issue of The EMBO Journal, Qi et al (2023) report a new model of two modules for the Hippo kinase cascade, providing new insights into this long-standing question.

Indexed as

Drosophila ProteinsNeoplasmsHippo Signaling PathwayHumansProtein Serine-Threonine KinasesSignal TransductionDrosophila ProteinsProtein Serine-Threonine Kinases

Identifiers

PMID37073568
PMCPMC10233370

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.