Evidence map›Paper›PMID 37073276›Full record

ArticlePeerJ2023

Cadmium nitrate and DNA methylation in gastropods: comparison between ovotestis and hepatopancreas.

George A Draghici, Cristina A Dehelean, Alina E Moaca, Marius L Moise, Iulia Pinzaru, Valentin N Vladut, Ioan Banatean-Dunea, Dragos Nica

Open access · goldAbstract read
In one paragraph

Article in PeerJ, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.6field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. DNA Methylation Machinery in Gastropod Mollusks.Life (Basel, Switzerland) · 2024
    Review
  6. Mass-Spectrometry-Based Research of Cosmetic Ingredients.Molecules (Basel, Switzerland) · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

George A DraghiciDepartment of Toxicology and Drug Industry, Faculty of Pharmacy, University of Medicine and Pharmacy of Timisoara, Timisoara, Timis, Romania.
Cristina A DeheleanDepartment of Toxicology and Drug Industry, Faculty of Pharmacy, University of Medicine and Pharmacy of Timisoara, Timisoara, Timis, Romania.
Alina E MoacaDepartment of Toxicology and Drug Industry, Faculty of Pharmacy, University of Medicine and Pharmacy of Timisoara, Timisoara, Timis, Romania.
Marius L MoisePremiere Hospital, Regina Maria Health Network, Timisoara, Timis, Romania.
Iulia PinzaruDepartment of Toxicology and Drug Industry, Faculty of Pharmacy, University of Medicine and Pharmacy of Timisoara, Timisoara, Timis, Romania.
Valentin N VladutThe National Institute of Research -Development for Machines and Installations Designed for Agriculture and Food Industry, Bucharest, Romania.
Ioan Banatean-DuneaFaculty of Agriculture, University of Life Sciences "King Mihai I" from Timişoara, Timisoara, Timis, Romania.
Dragos NicaResearch Center for Pharmaco-Toxicological Evaluations, Faculty of Pharmacy, University of Medicine and Pharmacy of Timisoara, Timisoara, Timis, Romania.
The National Institute of Research – Development for Machines and Installations Designed for Agriculture and Food Industry · ROWest University of Timişoara · RO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Dietary ingestion is the main route of exposure to hazardous contaminants in land animals. Cadmium, a high-profile toxic metal, affects living systems at different organismal levels, including major storage organs (liver, kidneys), key organs for species survival (gonads), and epigenetic networks regulating gene expression. 5-methylcytosine (5mC) is the most common and best-characterized epigenetic mark among different modified nucleosides in DNA. This important player in methylation-driven gene expression is impacted by cadmium in sentinel terrestrial vertebrates. However, limited information exists regarding its impact on macroinvertebrates, especially land snails commonly used as (eco)toxicological models. We first investigate the methylomic effects of dietary cadmium given as cadmium nitrate on terrestrial mollusks. Mature specimens of the common brown garden snail,

Indexed as

CadmiumCadmium CompoundsAnimalsDNA MethylationHepatopancreasNitratesCadmiumCadmium Compoundscadmium nitrateNitrates5-methylcytosineCadmiumCornu aspersumDNA methylationEcotoxicologyFoodLand snailsPollution

Identifiers

PMID37073276
PMCPMC10106083
OpenAlexW4365452944

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.