Evidence map›Paper›PMID 37073275›Full record

ArticlePeerJ2023

Alterations of the gut microbiota in type 2 diabetics with or without subclinical hypothyroidism.

Yanrong Lv, Rong Liu, Huaijie Jia, Xiaolan Sun, Yuhan Gong, Li Ma, Wei Qiu, Xiaoxia Wang

Open access · goldAbstract read
In one paragraph

Article in PeerJ, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 6 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Yanrong Lv *School of Public Health, Lanzhou University, Lanzhou, China.
Rong Liu *School of Public Health, Lanzhou University, Lanzhou, China.
Huaijie JiaState Key Laboratory of Veterinary of Etiological Biology, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou, China.
Xiaolan SunSchool of Public Health, Lanzhou University, Lanzhou, China.
Yuhan GongSchool of Public Health, Lanzhou University, Lanzhou, China.
Li MaSchool of Public Health, Lanzhou University, Lanzhou, China.
Wei QiuDepartment of Endocrinology, Xinxiang First People's Hospital, The Affiliated People's Hospital of Xinxiang Medical University, Xinxiang, China.
Xiaoxia WangSchool of Public Health, Lanzhou University, Lanzhou, China.
Lanzhou University · CNLanzhou Veterinary Research Institute · CNXinxiang Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Diabetes and thyroid dysfunction are two closely related endocrine diseases. Increasing evidences show that gut microbiota plays an important role in both glucose metabolism and thyroid homeostasis. Meanwhile, copy number variation (CNV) of host salivary Methods: High-throughput sequencing was used to analyze the gut microbiota of euthyroid T2D patients, T2D patients with SCH and healthy controls. Highly sensitive droplet digital PCR was used to measure AMY1 CN. Results: Our results revealed that T2D patients have lower gut microbial diversity, no matter with or without SCH. The characteristic taxa of T2D patients were Conclusion: This study identified characteristic bacterial taxa in gut microbiota of T2D patients with or without SCH, as well as the taxa associated with clinical indices in T2D patients. These results might be exploited in the prevention, diagnosis and treatment of endocrine disorders in the future.

Indexed as

Diabetes Mellitus, Type 2Gastrointestinal MicrobiomeHypothyroidismDNA Copy Number VariationsHumansDNA copy number variationGut microbiotaSalivary α-amylase geneSubclinical hypothyroidismType 2 Diabetes Mellitus

Identifiers

PMID37073275
PMCPMC10106085
OpenAlexW4365453474

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.