Evidence map›Paper›PMID 37073258›Full record

ReviewMarine life science & technology2021

The intriguing chemistry and biology of sulfur-containing natural products from marine microorganisms (1987-2020).

Yang Hai, Mei-Yan Wei, Chang-Yun Wang, Yu-Cheng Gu, Chang-Lun Shao

Abstract readReview
In one paragraph

Review in Marine life science & technology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers.

0numbers the graph read from it
0cells of the map it votes in
45citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

45 citing papers in PubMed.

  1. Article
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  4. Review
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  6. Review
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  8. B(CChemistry (Weinheim an der Bergstrasse, Germany) · 2025
    Article
  9. Article
  10. Talaroterpenoids A-F: Six NewMarine drugs · 2024
    Article
  11. Review
  12. Article
  13. Article
  14. Review
  15. Article
  16. 4-Fluoro-benzyl (IUCrData · 2024
    Article
  17. Tetramic acid-motif natural products from a marine fungusMarine life science & technology · 2024
    Article
  18. Enzymatic Resolution and Decarboxylative Functionalization of α-Sulfinyl Esters.Chemistry (Weinheim an der Bergstrasse, Germany) · 2024
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Yang HaiKey Laboratory of Marine Drugs, School of Medicine and Pharmacy, The Ministry of Education of China, Ocean University of China, Qingdao, 266003 China.
Mei-Yan WeiKey Laboratory of Marine Drugs, School of Medicine and Pharmacy, The Ministry of Education of China, Ocean University of China, Qingdao, 266003 China.
Chang-Yun WangKey Laboratory of Marine Drugs, School of Medicine and Pharmacy, The Ministry of Education of China, Ocean University of China, Qingdao, 266003 China.
Yu-Cheng GuSyngenta Jealott's Hill International Research Centre, Bracknell, Berkshire RG42 6EY UK.
Chang-Lun ShaoKey Laboratory of Marine Drugs, School of Medicine and Pharmacy, The Ministry of Education of China, Ocean University of China, Qingdao, 266003 China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Natural products derived from marine microorganisms have received great attention as a potential resource of new compound entities for drug discovery. The unique marine environment brings us a large group of sulfur-containing natural products with abundant biological functionality including antitumor, antibiotic, anti-inflammatory and antiviral activities. We reviewed all the 484 sulfur-containing natural products (non-sulfated) isolated from marine microorganisms, of which 59.9% are thioethers, 29.8% are thiazole/thiazoline-containing compounds and 10.3% are sulfoxides, sulfones, thioesters and many others. A selection of 133 compounds was further discussed on their structure-activity relationships, mechanisms of action, biosynthesis, and druggability. This is the first systematic review on sulfur-containing natural products from marine microorganisms conducted from January 1987, when the first one was reported, to December 2020. Supplementary Information: The online version contains supplementary material available at 10.1007/s42995-021-00101-2.

Indexed as

BioactivitiesMarine drugsMarine microorganismsMolecular diversitySulfur-containing natural products

Identifiers

PMID37073258
PMCPMC10077240

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.