Evidence map›Paper›PMID 37073135›Full record

ArticleExperimental biology and medicine (Maywood, N.J.)2023

Bioinformatics analysis of the genes associated with co-occurrence of heart failure and lung cancer.

Xiaoying Wang, Rui Song, Xin Li, Kai He, Linlin Ma, Yanfei Li

Open access · greenAbstract read
In one paragraph

Article in Experimental biology and medicine (Maywood, N.J.), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.9field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Heliyon · 2024
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

Xiaoying WangShanghai University of Medicine and Health Sciences Affiliated Zhoupu Hospital, Shanghai 201318, China.ORCID 0000-0001-9850-7800
Rui SongXuhui District Center for Disease Prevention and Control, Shanghai 200237, China.
Xin LiCardiovascular Medicine Department, East Hospital Affiliated to Tongji University, Shanghai 200120, China.
Kai HeShanghai University of Medicine and Health Sciences Affiliated Zhoupu Hospital, Shanghai 201318, China.
Linlin MaShanghai University of Medicine and Health Sciences Affiliated Zhoupu Hospital, Shanghai 201318, China.
Yanfei LiShanghai University of Medicine and Health Sciences Affiliated Zhoupu Hospital, Shanghai 201318, China.
Shanghai University of Traditional Chinese Medicine · CNShanghai East Hospital · CNShanghai Municipal Center For Disease Control Prevention · CNShanghai University of Medicine and Health Sciences · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Deaths of non-cardiac causes in patients with heart failure (HF) are on the rise, including lung cancer (LC). However, the common mechanisms behind the two diseases need to be further explored. This study aimed to improve understanding on the co-occurrence of LC and HF. In this study, gene expression profiles of HF (GSE57338) and LC (GSE151101) were comprehensively analyzed using the Gene Expression Omnibus database. Functional annotation, protein-protein interaction network, hub gene identification, and co-expression analysis were proceeded when the co-differentially expressed genes in HF and LC were identified. Among 44 common differentially expressed genes, 17 hub genes were identified to be associated with the co-occurrence of LC and HF; the hub genes were verified in 2 other data sets. Nine genes, including

Indexed as

Heart FailureLung NeoplasmsComputational BiologyDatabases, FactualHumansProtein Interaction Mapsbioinformatics analysisco-occurrencedifferentially expressed genesHeart failurehub geneslung cancer

Identifiers

PMID37073135
PMCPMC10484198
OpenAlexW4366352246

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.