Evidence map›Paper›PMID 37072867›Full record

ArticleStem cell research & therapy2023

The impact of SARS-CoV2 vaccines on the incidence of graft versus host disease in allogeneic hematopoietic stem cell transplant recipients: a single-center retrospective study.

Dat Ngo, Jason Chen, Jose Tinajero, Ahmed Aribi, Shukaib Arslan, Guido Marcucci, Ryotaro Nakamura, Monzr M Al Malki, Stephen J Forman, Sanjeet Dadwal and 1 more

Open access · goldAbstract readLetter
PubMed Full text at PMC Publisher
In one paragraph

Article in Stem cell research & therapy, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Dat NgoDepartment of Pharmacy, City of Hope Medical Center, 1500 E. Duarte Road, Duarte, CA, 91010, USA.
Jason ChenDepartment of Pharmacy, City of Hope Medical Center, 1500 E. Duarte Road, Duarte, CA, 91010, USA. jaschen@coh.org.ORCID 0000-0001-6523-7621
Jose TinajeroDepartment of Pharmacy, City of Hope Medical Center, 1500 E. Duarte Road, Duarte, CA, 91010, USA.
Ahmed AribiDepartment of Hematology and Hematopoietic Cell Transplantation, City of Hope, Duarte, CA, USA.
Shukaib ArslanDepartment of Hematology and Hematopoietic Cell Transplantation, City of Hope, Duarte, CA, USA.
Guido MarcucciDepartment of Hematology and Hematopoietic Cell Transplantation, City of Hope, Duarte, CA, USA.
Ryotaro NakamuraDepartment of Hematology and Hematopoietic Cell Transplantation, City of Hope, Duarte, CA, USA.
Monzr M Al MalkiDepartment of Hematology and Hematopoietic Cell Transplantation, City of Hope, Duarte, CA, USA.
Stephen J FormanDepartment of Hematology and Hematopoietic Cell Transplantation, City of Hope, Duarte, CA, USA.
Sanjeet DadwalDepartment of Infectious Diseases, City of Hope, Duarte, CA, USA.
Haris AliDepartment of Hematology and Hematopoietic Cell Transplantation, City of Hope, Duarte, CA, USA.
City of Hope · USCity Of Hope National Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study reports the incidence of chronic graft versus host disease (GvHD) in allogeneic hematopoietic stem cell transplant (alloHCT) recipients who received SARS-CoV2 vaccination. The overall rates of new and worsening chronic GvHD combined were 14%, with median time from vaccination to GVHD being approximately three to four weeks. A majority of the cases were of mild to moderate severity and primarily localized to either the skin, mouth, or joints. Prior chronic GVHD and recent transplant were associated with higher GVHD rates following COVID-19 vaccination. More prospective studies are needed to provide a definitive mechanism for the impact of SARS-CoV2 vaccination on alloHCT patients.

Indexed as

COVID-19COVID-19 VaccinesGraft vs Host DiseaseHematopoietic Stem Cell TransplantationHumansIncidenceRetrospective StudiesRNA, ViralSARS-CoV-2COVID-19 VaccinesRNA, ViralAllogeneic hematopoietic stem cell transplantationBNT162b2COVID-19 vaccineGraft-versus-host diseasemRNA-1273Severe acute respiratory syndrome coronavirus-2 (SARS-CoV2)

Identifiers

PMID37072867
PMCPMC10112306
OpenAlexW4366263869

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.