Evidence map›Paper›PMID 37072813›Full record

ReviewDiabetology & metabolic syndrome2023

Effect of vitamin D supplementation on type 2 diabetes biomarkers: an umbrella of interventional meta-analyses.

Vali Musazadeh, Zeynab Kavyani, Naghmeh Mirhosseini, Parvin Dehghan, Mahdi Vajdi

Open access · goldAbstract readReview
In one paragraph

Review in Diabetology & metabolic syndrome, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 2 pooled it
8.9field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 2 syntheses or guidelines pooled it, 35 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Vali MusazadehStudent Research Committee, Tabriz University of Medical Sciences, Tabriz, Iran.
Zeynab KavyaniStudent Research Committee, Tabriz University of Medical Sciences, Tabriz, Iran.
Naghmeh MirhosseiniSchool of Public Health, University of Saskatchewan, Saskatoon, SK, Canada.
Parvin DehghanAssociate of Nutrition, School of Nutrition and Food Sciences, Tabriz University of Medical Sciences, Tabriz, Iran. dehghan.nut@gmail.com.
Mahdi VajdiStudent Research Committee, Department of Community Nutrition, School of Nutrition and Food Science, Isfahan University of Medical Sciences, Isfahan, Iran. MV.vajdi@gmail.com.
Tabriz University of Medical Sciences · IRIsfahan University of Medical Sciences · IRUniversity of Saskatchewan · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundVitamin D supplementation exerts several supporting effects on improving glycemic status, however, results are inconclusive. Thus, in the present study, we aimed to conduct an umbrella of meta-analysis regarding the impact of vitamin D on type 2 diabetes (T2DM) biomarkers.

methodsThe Scopus, PubMed, Web of Science, Embase, and Google Scholar online databases were searched up to March 2022. All meta-analyses evaluating the impact of vitamin D supplementation on T2DM biomarkers were considered eligible. Overall, 37 meta-analyses were included in this umbrella meta-analysis.

resultsOur findings indicated that vitamin D supplementation significantly decreased fasting blood sugar (FBS) (WMD =  - 3.08; 95% CI: - 3.97, - 2.19, p < 0.001, and SMD =  - 0.26; 95% CI: - 0.38, - 0.14, p < 0.001), hemoglobin A1c (HbA1c) (WMD =  - 0.05; 95% CI: - 0.10, - 0.01, p = 0.016, and SMD =  - 0.16; 95% CI: - 0.27, - 0.05, p = 0.004), insulin concentrations (WMD =  - 2.62; 95% CI: - 4.11, - 1.13; p < 0.001, and SMD =  - 0.33; 95% CI: - 0.56, - 0.11, p = 0.004), and homeostatic model assessment for insulin resistance (HOMA-IR) (WMD =  - 0.67; 95% CI: - 1.01, - 0.32, p < 0.001, and SMD =  - 0.31; 95% CI: - 0.46, - 0.16, p < 0.001).

conclusionThis umbrella meta-analysis proposed that vitamin D supplementation may improve T2DM biomarkers.

Indexed as

DiabetesGlycemic indicesUmbrella meta-analysisVitamin D

Identifiers

PMID37072813
PMCPMC10114333
OpenAlexW4366351701

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.