Evidence map›Paper›PMID 37072748›Full record

ArticleJournal of translational medicine2023

The "Great Debate" at Melanoma Bridge 2022, Naples, December 1st-3rd, 2022.

Paolo A Ascierto, Christian Blank, Alexander M Eggermont, Claus Garbe, Jeffrey E Gershenwald, Omid Hamid, Axel Hauschild, Jason J Luke, Janice M Mehnert, Jeffrey A Sosman and 6 more

Open access · goldAbstract read
In one paragraph

Article in Journal of translational medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.7field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 12 institutions in 5 countries.

Paolo A AsciertoDepartment of Melanoma, Cancer Immunotherapy and Innovative Therapy, Istituto Nazionale Tumori IRCCS "Fondazione G. Pascale", Naples, Italy. paolo.ascierto@gmail.com.ORCID 0000-0002-8322-475X
Christian BlankNetherlands Cancer Institute, Amsterdam, The Netherlands.
Alexander M EggermontUniversity Medical Center Utrecht & Princess Maxima Center, Utrecht, The Netherlands.
Claus GarbeCenter for Dermatooncology, Department of Dermatology, Eberhard Karls University, Tuebingen, Germany.
Jeffrey E GershenwaldDepartment of Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Omid HamidThe Angeles Clinic and Research Institute, A Cedars-Sinai Affiliate, Los Angeles, CA, USA.
Axel HauschildDepartment of Dermatology, University of Kiel, Kiel, Germany.
Jason J LukeUniversity of Pittsburgh Medical Center (UPMC) Hillman Cancer Center, Pittsburgh, PA, USA.
Janice M MehnertPerlmutter Cancer Center of NYU Langone/NYU Grossman School of Medicine, New York, NY, USA.
Jeffrey A SosmanRobert H Lurie Comprehensive Cancer Center, Northwestern University Medical Center, Chicago, IL, USA.
Hussein A TawbiMD Anderson Brain Metastasis Clinic UT, MD Anderson Cancer Center, Houston, TX, USA.
Mario MandalàUniversity of Perugia, Perugia, Italy.
Alessandro TestoriImage regenerative clinic Milan, Italy; EORTC Melanoma Group, Brussels, Belgium.
Corrado CaracòDivision of Surgery of Melanoma and Skin Cancer, Istituto Nazionale Tumori "Fondazione Pascale" IRCCS, Naples, Italy.
Iman OsmanRudolf L. Baer, NYU Langone Medical Center, New York, NY, USA.
Igor PuzanovDepartment of Medicine, Roswell Park Comprehensive Cancer Center, Buffalo, NY, USA.
Istituto Nazionale Tumori IRCCS "Fondazione G. Pascale" · ITNYU Langone Health · USThe University of Texas MD Anderson Cancer Center · USAngeles Clinic and Research Institute · USChristian-Albrechts-Universität zu Kiel · DEEuropean Organisation for Research and Treatment of Cancer · NLNorthwestern University · USRoswell Park Comprehensive Cancer Center · USThe Netherlands Cancer Institute · NLUniversity Medical Center Utrecht · NLUniversity of Perugia · ITUPMC Hillman Cancer Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The Great Debate session at the 2022 Melanoma Bridge congress (December 1-3) featured counterpoint views from leading experts on five contemporary topics of debate in the management of melanoma. The debates considered the choice of anti-lymphocyte-activation gene (LAG)-3 therapy or ipilimumab in combination with anti-programmed death (PD)-1 therapy, whether anti-PD-1 monotherapy is still acceptable as a comparator arm in clinical trials, whether adjuvant treatment of melanoma is still a useful treatment option, the role of adjuvant therapy in stage II melanoma, what role surgery will continue to have in the treatment of melanoma. As is customary in the Melanoma Bridge Great Debates, the speakers are invited by the meeting Chairs to express one side of the assigned debate and the opinions given may not fully reflect personal views. Audiences voted in favour of either side of the argument both before and after each debate.

Indexed as

MelanomaSkin NeoplasmsCombined Modality TherapyHumansImmunotherapyIpilimumabIpilimumabAdjuvantAnti-PD-1ImmunotherapyMelanomaNeoadjuvantSurgeryTargeted therapy

Identifiers

PMID37072748
PMCPMC10114457
OpenAlexW4366266963

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.