Evidence map›Paper›PMID 37072740›Full record

ArticleBMC pediatrics2023

Children hospitalized with community-acquired pneumonia complicated by effusion: a single-centre retrospective cohort study.

Gelila Alemayheu, Claire S J Lee, Laura K Erdman, Jacqueline Wong, Candy Rutherford, Marek Smieja, Sarah Khan, Jeffrey M Pernica

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC pediatrics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Gelila AlemayheuSchool of Medicine, Western University, London, ON, Canada.
Claire S J LeeFaculty of Medicine, University of Toronto, Toronto, ON, Canada.
Laura K ErdmanDepartment of Pediatrics, Faculty of Health Sciences, McMaster University, 1280 Main St West, L8S 4K1, Hamilton, ON, Canada.
Jacqueline WongDepartment of Pediatrics, Faculty of Health Sciences, McMaster University, 1280 Main St West, L8S 4K1, Hamilton, ON, Canada.
Candy RutherfordHamilton Regional Laboratory Medicine Program, Hamilton, ON, Canada.
Marek SmiejaDepartment of Pathology and Molecular Medicine, Faculty of Health Sciences, McMaster University, Hamilton, ON, Canada.
Sarah KhanDepartment of Pediatrics, Faculty of Health Sciences, McMaster University, 1280 Main St West, L8S 4K1, Hamilton, ON, Canada.
Jeffrey M PernicaDepartment of Pediatrics, Faculty of Health Sciences, McMaster University, 1280 Main St West, L8S 4K1, Hamilton, ON, Canada. pernica@mcmaster.ca.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo describe children hospitalized with community-acquired pneumonia complicated by effusion (cCAP).

designRetrospective cohort study.

settingA Canadian children's hospital.

participantsChildren without significant medical comorbidities aged < 18 years admitted from January 2015-December 2019 to either the Paediatric Medicine or Paediatric General Surgery services with any pneumonia discharge code who were documented to have an effusion/empyaema using ultrasound. OUTCOME MEASURES: Length of stay; admission to the paediatric intensive care unit; microbiologic diagnosis; antibiotic use.

resultsThere were 109 children without significant medical comorbidities hospitalized for confirmed cCAP during the study period. Their median length of stay was 9 days (Q1-Q3 6-11 days) and 35/109 (32%) were admitted to the paediatric intensive care unit. Most (89/109, 74%) underwent procedural drainage. Length of stay was not associated with effusion size but was associated with time to drainage (0.60 days longer stay per day delay in drainage, 95%CI 0.19-1.0 days). Microbiologic diagnosis was more often made via molecular testing of pleural fluids (43/59, 73%) than via blood culture (12/109, 11%); the main aetiologic pathogens were S. pneumoniae (40/109, 37%), S. pyogenes (15/109, 14%), and S. aureus (7/109, 6%). Discharge on a narrow spectrum antibiotic (i.e. amoxicillin) was much more common when the cCAP pathogen was identified as compared to when it was not (68% vs. 24%, p < 0.001).

conclusionsChildren with cCAP were commonly hospitalized for prolonged periods. Prompt procedural drainage was associated with shorter hospital stays. Pleural fluid testing often facilitated microbiologic diagnosis, which itself was associated with more appropriate antibiotic therapy.

Indexed as

Community-Acquired InfectionsPleural EffusionPneumoniaAnti-Bacterial AgentsCanadaChildHumansInfantRetrospective StudiesStaphylococcus aureusStreptococcus pneumoniaeStreptococcus pyogenesAnti-Bacterial AgentsEpidemiologyMicrobiologyPleural effusionPneumoniaProcedural drainage

Identifiers

PMID37072740
PMCPMC10113124

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.