Evidence map›Paper›PMID 37072693›Full record

ArticleGenetics, selection, evolution : GSE2023

Variation in the proportion of the segregating genome shared between full-sibling cattle and sheep.

David Kenny, Donagh P Berry, Thierry Pabiou, Pierce Rafter

Open access · goldAbstract read
In one paragraph

Article in Genetics, selection, evolution : GSE, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.9field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

David Kenny *Animal and Grassland Research and Innovation Centre, Teagasc, Moorepark, Fermoy, Ireland.
Donagh P BerryAnimal and Grassland Research and Innovation Centre, Teagasc, Moorepark, Fermoy, Ireland. Donagh.Berry@teagasc.ie.
Thierry PabiouSheep Ireland, Highfield House, Shinagh, Bandon, Ireland.
Pierce Rafter *Animal and Grassland Research and Innovation Centre, Teagasc, Moorepark, Fermoy, Ireland.
Teagasc - The Irish Agriculture and Food Development Authority · IE

Funding

Science Foundation Ireland 16/RC/3835
6 · The paper itself

Abstract

The construction of covariance matrices that account for the genetic relationships among individuals, using pedigree or genotype data, is integral to genetic evaluations, which are now routinely used in the field of animal breeding. The objective of the present study was to estimate the standard deviation in the proportion of the segregating genome that is shared between pairs of full-sibling cattle and sheep independently. Post edits, genotype data comprising 46,069 autosomal single nucleotide polymorphisms (SNPs) were available for 4532 unique full-sibling sheep pairs, as well as for their respective parents. Post edits, genotypes from 50,493 autosomal SNPs were also available for 10,000 unique full-sibling cattle pairs, as well as their respective parents. Genomic relationship matrices were constructed for the sheep and cattle populations, separately. After accounting for both parental genomic inbreeding and the genomic relationship between both parents, the standard deviation in full-sibling cattle and sheep genomic relationships was 0.040 and 0.037 units, respectively. In addition, the intercept value from a linear regression model which regressed each full-sibling genomic relationship on both sire and dam inbreeding, as well as the genomic relationship between the parents, was 0.499 (0.001) for sheep and 0.500 (0.001) for cattle, conforming to the expectation that full-siblings, on average, share 50% of their segregating genome.

Indexed as

GenomeSiblingsAnimalsCattleGenomicsGenotypeHumansInbreedingPedigreePolymorphism, Single NucleotideSheep

Identifiers

PMID37072693
PMCPMC10111659
OpenAlexW4366278961

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.