Evidence map›Paper›PMID 37072646›Full record

ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2023

METTL3 Mediates Epithelial-Mesenchymal Transition by Modulating FOXO1 mRNA N

Yang Feng, Ping Yuan, Hongjuan Guo, Liming Gu, Zhao Yang, Jian Wang, Wei Zhu, Qi Zhang, Jianping Cao, Lili Wang and 1 more

Open access · goldAbstract read
In one paragraph

Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
4.5field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 29 citations in OpenAlex.

  1. Review
  2. Emerging roles of RNA mInternational journal of oncology · 2026
    Review
  3. Article
  4. Article
  5. Article
  6. Review
  7. Review
  8. Article
  9. Article
  10. Article
  11. METTL3-mediated mScientific reports · 2025
    Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 1 country.

Yang FengState Key Laboratory of Radiation Medicine and Protection, School of Radiation Medicine and Protection, Medical College of Soochow University, Suzhou, 215123, China.
Ping YuanDepartment of Cardio-Pulmonary Circulation, Shanghai Pulmonary Hospital, School of Medicine, Tongji University, Shanghai, 200030, China.
Hongjuan GuoState Key Laboratory of Radiation Medicine and Protection, School of Radiation Medicine and Protection, Medical College of Soochow University, Suzhou, 215123, China.
Liming GuState Key Laboratory of Radiation Medicine and Protection, School of Radiation Medicine and Protection, Medical College of Soochow University, Suzhou, 215123, China.
Zhao YangDepartment of Respiratory Medicine, Suzhou Science & Technology Town Hospital, Suzhou, 215153, China.
Jian WangDepartment of Radiotherapy, the Affiliated Jiangyin People's Hospital of Nantong University, Jiangyin, 214400, China.
Wei ZhuState Key Laboratory of Radiation Medicine and Protection, School of Radiation Medicine and Protection, Medical College of Soochow University, Suzhou, 215123, China.
Qi ZhangState Key Laboratory of Radiation Medicine and Protection, School of Radiation Medicine and Protection, Medical College of Soochow University, Suzhou, 215123, China.
Jianping CaoState Key Laboratory of Radiation Medicine and Protection, School of Radiation Medicine and Protection, Medical College of Soochow University, Suzhou, 215123, China.
Lili WangDepartment of Radiotherapy, the First Affiliated Hospital of Soochow University, Suzhou, 215006, China.
Yang JiaoState Key Laboratory of Radiation Medicine and Protection, School of Radiation Medicine and Protection, Medical College of Soochow University, Suzhou, 215123, China.ORCID 0000-0002-5452-5553
Soochow University · CNJiangyin People's Hospital · CNSuzhou University of Science and Technology · CNTongji University · CN

Funding

Distinguished Medical Expert in Jiangsu Province JSTPYXZJ2021006Innovative and Entrepreneurial Talent in Jiangsu Province JSSCRC2021568Key Laboratory of Radiation Medicine and Protection, Soochow University GZN1202002Key Scientific Research Projects of Jiangsu Provincial Health Commission ZD2021053National Key R&D Program of China 2022YFC2503700National Key R&D Program of China 2022YFC2503703National Natural Science Foundation of China 81870042National Natural Science Foundation of China 82073476National Natural Science Foundation of China U1967220Priority Academic Program Development (PAPD) of Jiangsu Higher Education Institutions
6 · The paper itself

Abstract

The biological roles of epithelial-mesenchymal transition (EMT) in the pathogenesis of radiation-induced lung injury (RILI) have been widely demonstrated, but the mechanisms involved have been incompletely elucidated. N

Indexed as

Lung InjuryRadiation InjuriesAnimalsEpithelial-Mesenchymal TransitionForkhead Box Protein O1HumansMethyltransferasesMiceProto-Oncogene Proteins c-aktRatsRNARNA-Binding ProteinsRNA, MessengerForkhead Box Protein O1FOXO1 protein, humanMethyltransferasesMETTL3 protein, humanProto-Oncogene Proteins c-aktRNARNA-Binding ProteinsRNA, MessengerYTHDF2 protein, humanepithelial-mesenchymal transition (EMT)forkhead box O1 (FOXO1)ionizing radiation (IR)methyltransferase-like 3 (METTL3)N6-methyladenosine (m6A)radiation-induced lung injury (RILI)

Identifiers

PMID37072646
PMCPMC10265050
OpenAlexW4366351661

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.