Evidence map›Paper›PMID 37072598›Full record

ArticlePharmacoEconomics2023

The Value of Health in a Cost-Effectiveness Analysis: Theory Versus Practice.

Bram Wouterse, Pieter van Baal, Matthijs Versteegh, Werner Brouwer

Open access · hybridAbstract read
In one paragraph

Article in PharmacoEconomics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
24.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 45 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Review
  5. Diagnostic value of MRI for posttreatment surveillance of early-stage (I-II) glottic larynx cancer.Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] · 2026
    Article
  6. Article
  7. Article
  8. Nothing about us, without us? A reflection on and call for involving children in the process of valuing child health.The European journal of health economics : HEPAC : health economics in prevention and care · 2026
    Article
  9. The value of health and well-being from a societal perspective: A willingness to pay experiment in the Netherlands.The European journal of health economics : HEPAC : health economics in prevention and care · 2026
    Article
  10. Review
  11. Article
  12. Article
  13. Review
  14. The economic burden of brucellosis in Western Iran.Tropical medicine and health · 2025
    Article
  15. Article
  16. Article
  17. Establishing a Research Agenda for Physiotherapy in Portugal: A Delphi Study.Physiotherapy research international : the journal for researchers and clinicians in physical therapy · 2025
    Article
  18. Observational
  19. Benefits beyond health in the willingness to pay for a quality-adjusted life-year.The European journal of health economics : HEPAC : health economics in prevention and care · 2025
    Article
  20. The Future of Arthroplasty in the Spine.International journal of spine surgery · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Bram WouterseErasmus School of Health Policy and Management (ESHPM), Erasmus University Rotterdam, P.O. Box 1738, 3000 DR, Rotterdam, The Netherlands. wouterse@eshpm.eur.nl.ORCID http://orcid.org/0000-0002-8432-8841
Pieter van BaalErasmus School of Health Policy and Management (ESHPM), Erasmus University Rotterdam, P.O. Box 1738, 3000 DR, Rotterdam, The Netherlands.ORCID http://orcid.org/0000-0001-9913-2393
Matthijs VersteeghInstitute for Medical Technology Assessment (iMTA), Erasmus University Rotterdam, Rotterdam, The Netherlands.ORCID http://orcid.org/0000-0003-4804-235X
Werner BrouwerErasmus School of Health Policy and Management (ESHPM), Erasmus University Rotterdam, P.O. Box 1738, 3000 DR, Rotterdam, The Netherlands.ORCID http://orcid.org/0000-0002-0476-8397
Erasmus University Rotterdam · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A cost-effectiveness analysis has become an important method to inform allocation decisions and reimbursement of new technologies in healthcare. A cost-effectiveness analysis requires a threshold to which the cost effectiveness of a new intervention can be compared. In principle, the threshold ought to reflect opportunity costs of reimbursing a new technology. In this paper, we contrast the practical use of this threshold within a CEA with its theoretical underpinnings. We argue that several assumptions behind the theoretical models underlying this threshold are violated in practice. This implies that a simple application of the decision rules of CEA using a single estimate of the threshold does not necessarily improve population health or societal welfare. Conceptual differences regarding the interpretation of the threshold, widely varying estimates of its value, and an inconsistent use within and outside the healthcare sector are important challenges in informing policy makers on optimal reimbursement decision and setting appropriate healthcare budgets.

Indexed as

Cost-Effectiveness AnalysisDelivery of Health CareBudgetsCost-Benefit AnalysisHumansModels, Theoretical

Identifiers

PMID37072598
PMCPMC10163089
OpenAlexW4366263198

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.