Evidence map›Paper›PMID 37072583›Full record

ArticleArchives of gynecology and obstetrics2023

Caprini assessment utilization and impact on patient safety in gynecologic surgery.

Gregory K Lewis, Aaron C Spaulding, Emily Brennan, Jamie N Bakkum-Gamez, Tri A Dinh, Dorin T Colibaseanu, John D Casler, Michael A Edwards

Abstract read
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In one paragraph

Article in Archives of gynecology and obstetrics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.7field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 6 citations in OpenAlex.

  1. [Independent Risk Factors for Venous Thromboembolism After Gynecological Surgery and the Predictive Value of Postoperative D-Dimer].Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Gregory K LewisDepartment of Surgical Gynecology, Mayo Clinic Florida, Mayo Alix School of Medicine, 4500 San Pablo Road S, Jacksonville, FL, 32224, USA. gklewlew@gmail.com.ORCID 0000-0003-4922-1165
Aaron C SpauldingMayo Clinic Florida, Division of Health Care Delivery Research, Jacksonville, FL, 32224, USA.
Emily BrennanMayo Clinic Florida, Division of Health Care Delivery Research, Jacksonville, FL, 32224, USA.
Jamie N Bakkum-GamezDepartment of Obstetrics and Gynecology, Mayo Clinic Rochester, Rochester, MN, 55905, USA.
Tri A DinhDepartment of Surgical Gynecology, Mayo Clinic Florida, Mayo Alix School of Medicine, 4500 San Pablo Road S, Jacksonville, FL, 32224, USA.
Dorin T ColibaseanuDivision of Colorectal Surgery, Mayo Clinic Florida, Jacksonville, FL, 32224, USA.
John D CaslerDepartment of Otolaryngology, Mayo Clinic Florida, Jacksonville, FL, 32224, USA.
Michael A EdwardsDepartment of Surgery, Mayo Clinic Florida, Mayo Alix School of Medicine, 4500 San Pablo Road S, Jacksonville, FL, 32224, USA. edwards.michael@mayo.edu.
Mayo Clinic in Florida · USJacksonville College · USWinnMed · USMayo Clinic · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposePostoperative venous thromboembolism (VTE) can potentially be associated with significant morbidity, mortality, and healthcare costs. The aim of this study was to determine the utilization of Caprini guideline indicated VTE in elective gynecologic surgery patients and its impact on postoperative VTE and bleeding complications.

methodsThis was a retrospective cohort study of elective gynecologic surgical procedures performed between January 1, 2016, and May 31, 2021. Two study cohorts were generated: (1) those who received and (2) those who did not receive VTE prophylaxis based on Caprini score risk stratification. Outcome measures were then compared between the study cohorts and included the development of a VTE up to 90-days postoperatively. Secondary outcome measures included postoperative bleeding events.

resultsA total of 5471 patients met inclusion criteria and the incidence of VTE up to 90 days postoperatively was 1.04%. Overall, 29.6% of gynecologic surgery patients received Caprini score-based guideline VTE prophylaxis. 39.2% of patients that met high-risk VTE criteria (Caprini > 5) received appropriate Caprini score-based prophylaxis. In multivariate regression analysis, the American Society of Anesthesiologists (ASA) score (OR 2.37, CI 1.27-4.45, p < 0.0001) and Caprini score (OR 1.13, CI 1.03-1.24, p = 0.008) predicted postoperatively VTE occurrence. Increasing Charlson comorbidity score (OR 1.39, CI 1.31-1.47, P < 0.001) ASA score (OR 1.36, CI 1.19-1.55, P < 0.001) and Caprini score (OR 1.10, CI 1.08-1.13, P < 0.001) were associated with increased odds of receiving appropriate inpatient VTE prophylaxis.

conclusionWhile the overall incidence of VTE was low in this cohort, enhanced adherence to risk-based practice guidelines may provide more patient benefit than harm to postoperative gynecologic patients.

Indexed as

Venous ThromboembolismFemaleGynecologic Surgical ProceduresHemorrhageHumansPatient SafetyPostoperative ComplicationsRetrospective StudiesRisk AssessmentRisk FactorsCaprini scoreGynecologic surgeryPostoperative bleeding riskVenous thromboembolism

Identifiers

PMID37072583
OpenAlexW4366261925

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.