ReviewNeurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics2023
Advances in the Diagnosis and Treatment of Pediatric Arterial Ischemic Stroke.
Review in Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed, 1 synthesis or guideline pooled it, 31 citations in OpenAlex.
- [Guide to the treatment of paediatric strokes. Iberoamerican Academy of Pediatric Neurology].Revista de neurologia · 2024Guideline
- CCR1 as a potential regulator of neutrophil-mediated pathogenesis in post-acute ischemic stroke: a multi-omics Mendelian randomization.Clinical epigenetics · 2026Article
- Article
- RehabMate: an explainable framework for action detection and corrective feedback in pediatric stroke rehabilitation.Scientific reports · 2026Article
- Article
- The changes of serum inflammatory cytokines in patients with hemiplegia after ischemic stroke and the rehabilitation effects.Journal of medical biochemistry · 2025Article
- Does Time and Experience Matter in Pediatric Arterial Ischemic Stroke (AIS) Intervention in Patients with an Initial Clinical Presentation of Mild/Moderate Severity? Long-Term Follow-Up Experience of a Single Tertiary Clinic.Children (Basel, Switzerland) · 2025Article
- Targeting TXNIP for neuroprotection: A novel approach to reducing inflammation and promoting recovery in ischemic stroke.Biomolecules & biomedicine · 2025Article
- Prognostic evaluation of ischemic stroke complicated by pulmonary infection using SII and CALLY indices.American journal of translational research · 2025Article
- Article
- Single-Center Incidence and Patterns of Stroke in Early Renal Anhydramnios After Serial Amnioinfusions.The Journal of pediatrics · 2024Article
- Decompressive hemicraniectomy in pediatric malignant arterial ischemic stroke: a case-based review.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2023Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Though rare, stroke in infants and children is an important cause of mortality and chronic morbidity in the pediatric population. Neuroimaging advances and implementation of pediatric stroke care protocols have led to the ability to rapidly diagnose stroke and in many cases determine the stroke etiology. Though data on efficacy of hyperacute therapies, such as intravenous thrombolysis and mechanical thrombectomy, in pediatric stroke are limited, feasibility and safety data are mounting and support careful consideration of these treatments for childhood stroke. Recent therapeutic advances allow for targeted stroke prevention efforts in high-risk conditions, such as moyamoya, sickle cell disease, cardiac disease, and genetic disorders. Despite these exciting advances, important knowledge gaps persist, including optimal dosing and type of thrombolytic agents, inclusion criteria for mechanical thrombectomy, the role of immunomodulatory therapies for focal cerebral arteriopathy, optimal long-term antithrombotic strategies, the role of patent foramen ovale closure in pediatric stroke, and optimal rehabilitation strategies after stroke of the developing brain.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.