Evidence map›Paper›PMID 37072539›Full record

ArticleMagma (New York, N.Y.)2023

Near-wall hemodynamic parameters quantification in in vitro intracranial aneurysms with 7 T PC-MRI.

Antoine Sache, Philippe Reymond, Olivier Brina, Bernd Jung, Mohamed Farhat, Maria Isabel Vargas

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Magma (New York, N.Y.), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.8field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 4 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Antoine SacheDepartment of Mechanical Engineering, Ecole Polytechnique Fédérale de Lausanne, Lausanne, Switzerland. antoine.sache@epfl.ch.ORCID http://orcid.org/0000-0001-9358-5236
Philippe ReymondDivision of Neuroradiology, Geneva University Hospital, University of Geneva, Geneva, Switzerland.
Olivier BrinaDivision of Neuroradiology, Geneva University Hospital, University of Geneva, Geneva, Switzerland.
Bernd JungDepartment of Diagnostic, Interventional and Paediatric Radiology, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.
Mohamed FarhatDepartment of Mechanical Engineering, Ecole Polytechnique Fédérale de Lausanne, Lausanne, Switzerland.
Maria Isabel VargasDivision of Neuroradiology, Geneva University Hospital, University of Geneva, Geneva, Switzerland.
University of Geneva · CHÉcole Polytechnique Fédérale de Lausanne · CHUniversity of Bern · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveWall shear stress (WSS) and its derived spatiotemporal parameters have proven to play a major role on intracranial aneurysms (IAs) growth and rupture. This study aims to demonstrate how ultra-high field (UHF) 7 T phase contrast magnetic resonance imaging (PC-MRI) coupled with advanced image acceleration techniques allows a highly resolved visualization of near-wall hemodynamic parameters patterns in in vitro IAs, paving the way for more robust risk assessment of their growth and rupture. MATERIALS AND

methodsWe performed pulsatile flow measurements inside three in vitro models of patient-specific IAs using 7 T PC-MRI. To this end, we built an MRI-compatible test bench, which faithfully reproduced a typical physiological intracranial flow rate in the models.

resultsThe ultra-high field 7 T images revealed WSS patterns with high spatiotemporal resolution. Interestingly, the high oscillatory shear index values were found in the core of low WSS vortical structures and in flow stream intersecting regions. In contrast, maxima of WSS occurred around the impinging jet sites.

conclusionsWe showed that the elevated signal-to-noise ratio arising from 7 T PC-MRI enabled to resolve high and low WSS patterns with a high degree of detail.

Indexed as

Intracranial AneurysmBlood Flow VelocityHemodynamicsHumansImaging, Three-DimensionalMagnetic Resonance ImagingStress, Mechanical7 T phase contrast MRIHemodynamicsIntracranial aneurysmsIn vitro modelsWall shear stress

Identifiers

PMID37072539
PMCPMC10140017
OpenAlexW4366337354

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.