Evidence map›Paper›PMID 37071547›Full record

ArticleThe journal of physical chemistry. B2023

Enhanced Antifungal Activity of Amphotericin B Bound to Albumin: A "Trojan Horse" Effect of the Protein.

Ewa Grela, Sylwia Stączek, Monika Nowak, Bozena Pawlikowska-Pawlega, Agnieszka Zdybicka-Barabas, Sebastian Janik, Małgorzata Cytryńska, Wojciech Grudzinski, Wieslaw I Gruszecki, Rafal Luchowski

Open access · hybridAbstract read
In one paragraph

Article in The journal of physical chemistry. B, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.6field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Ewa GrelaDepartment of Biophysics, Institute of Physics, Faculty of Mathematics, Physics and Informatics, Maria Curie-Sklodowska University, 20-031 Lublin, Poland.ORCID 0000-0002-1667-6780
Sylwia StączekDepartment of Immunobiology, Faculty of Biology and Biotechnology, Institute of Biological Sciences, Maria Curie-Sklodowska University, 20-033 Lublin, Poland.ORCID 0000-0002-4879-1329
Monika NowakDepartment of Biophysics, Institute of Physics, Faculty of Mathematics, Physics and Informatics, Maria Curie-Sklodowska University, 20-031 Lublin, Poland.
Bozena Pawlikowska-PawlegaDepartment of Functional Anatomy and Cytobiology, Faculty of Biology and Biotechnology, Institute of Biological Sciences, Maria Curie-Sklodowska University, 20-033 Lublin, Poland.
Agnieszka Zdybicka-BarabasDepartment of Immunobiology, Faculty of Biology and Biotechnology, Institute of Biological Sciences, Maria Curie-Sklodowska University, 20-033 Lublin, Poland.
Sebastian JanikDepartment of Biophysics, Institute of Physics, Faculty of Mathematics, Physics and Informatics, Maria Curie-Sklodowska University, 20-031 Lublin, Poland.
Małgorzata CytryńskaDepartment of Immunobiology, Faculty of Biology and Biotechnology, Institute of Biological Sciences, Maria Curie-Sklodowska University, 20-033 Lublin, Poland.
Wojciech GrudzinskiDepartment of Biophysics, Institute of Physics, Faculty of Mathematics, Physics and Informatics, Maria Curie-Sklodowska University, 20-031 Lublin, Poland.
Wieslaw I GruszeckiDepartment of Biophysics, Institute of Physics, Faculty of Mathematics, Physics and Informatics, Maria Curie-Sklodowska University, 20-031 Lublin, Poland.ORCID 0000-0002-8245-3913
Rafal LuchowskiDepartment of Biophysics, Institute of Physics, Faculty of Mathematics, Physics and Informatics, Maria Curie-Sklodowska University, 20-031 Lublin, Poland.ORCID 0000-0003-1156-8059
Maria Curie-Skłodowska University · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Amphotericin B (AmB) is a life-saving and widely used antifungal antibiotic, but its therapeutic applicability is limited due to severe side effects. Here, we report that the formulation of the drug based on a complex with albumin (BSA) is highly effective against

Indexed as

Amphotericin BAntifungal AgentsAlbuminsAnti-Bacterial AgentsCandida albicansAlbuminsAmphotericin BAnti-Bacterial AgentsAntifungal Agents

Identifiers

PMID37071547
PMCPMC10150355
OpenAlexW4366236235

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.