Evidence map›Paper›PMID 37071341›Full record

ReviewCell stress & chaperones2023

Tenth International Symposium on the Hsp90 chaperone machine : Switzerland, October 19-23, 2022.

Adrienne L Edkins, Markus Zweckstetter, Ritwick Sawarkar

Abstract readReview
In one paragraph

Review in Cell stress & chaperones, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Adrienne L EdkinsBiomedical Biotechnology Research Unit (BioBRU), Department of Microbiology and Biochemistry, Rhodes University, Makhanda, South Africa. a.edkins@ru.ac.za.
Markus ZweckstetterGerman Center for Neurodegenerative Diseases (DZNE), Göttingen, Germany.
Ritwick SawarkarMedical Research Council (MRC) and Department of Genetics, University of Cambridge, Cambridge, UK.

Funding

Medical Research Council MC_UU_00025/8
6 · The paper itself

Abstract

Hsp90 is a molecular chaperone responsible for regulating proteostasis under physiological and pathological conditions. Its central role in a range of diseases and potential as a drug target has focused efforts to understand its mechanisms and biological functions and to identify modulators that may form the basis for therapies. The 10

Indexed as

COVID-19PandemicsHSP90 Heat-Shock ProteinsHumansMolecular ChaperonesProtein BindingSwitzerlandHSP90 Heat-Shock ProteinsMolecular ChaperonesCochaperones and client proteinsHsp90Molecular chaperone

Identifiers

PMID37071341
PMCPMC10111302

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.