Evidence map›Paper›PMID 37071124›Full record

ArticleThe Journal of experimental medicine2023

CTLA4 prohibits T cells from cross-dressing.

Noémie Paillon, Claire Hivroz

Abstract readComment
PubMed Full text at PMC Publisher
In one paragraph

Article in The Journal of experimental medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. CD28/PD1 co-expression: dual impact on CD8Journal of experimental & clinical cancer research : CR · 2023
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Noémie PaillonInstitut Curie , Paris Sciences et Lettres University, Inserm U932, Immunity and Cancer , Paris, France.ORCID 0000-0002-6848-3016
Claire HivrozInstitut Curie , Paris Sciences et Lettres University, Inserm U932, Immunity and Cancer , Paris, France.ORCID 0000-0002-6794-2890

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this issue of JEM, Xiaozheng Xu et al. (2023. J. Exp. Med.https://doi.org/10.1084/jem.20221391) report that the inhibitory protein CTLA4 internalizes in cis the B7 stimulatory molecules previously "gnawed" by T cells from antigen-presenting cells (APCs) and in doing so prevents stimulatory T-T interactions.

Indexed as

Antigen-Presenting CellsT-LymphocytesBandagesCTLA-4 AntigenCTLA-4 Antigen

Identifiers

PMID37071124
PMCPMC10120349

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.