Evidence map›Paper›PMID 37071015›Full record

ArticleJournal of virology2023

Peripheral Nerve Injury Induced by Japanese Encephalitis Virus in C57BL/6 Mouse.

Huan Yang, Xiaoli Wang, Zhao Wang, Guowei Wang, Shihong Fu, Fan Li, Liping Yang, Yanping Yuan, Kaichun Shen, Huanyu Wang and 1 more

Open access · hybridAbstract read
In one paragraph

Article in Journal of virology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
3.5field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Flaviviruses-Induced Neurological Sequelae.Pathogens (Basel, Switzerland) · 2024
    Review
  8. Article
  9. Host Factor Rab4b PromotesMicroorganisms · 2024
    Article
  10. Article
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Huan Yang *General Hospital of Ningxia Medical University, Yinchuan, China.
Xiaoli Wang *The No. 1 People's Hospital of Shizuishan, Shizuishan, China.
Zhao WangThe Second Affiliated Hospital of Air Force Medical University, Xi'an, China.
Guowei WangNingxia Medical University, Yinchuan, China.
Shihong FuDepartment of Viral Encephalitis, NHC Key Laboratory of Biosafety, National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China.
Fan LiDepartment of Viral Encephalitis, NHC Key Laboratory of Biosafety, National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China.
Liping YangNingxia Medical University, Yinchuan, China.
Yanping YuanNingxia Medical University, Yinchuan, China.
Kaichun ShenNingxia Medical University, Yinchuan, China.
Huanyu WangDepartment of Viral Encephalitis, NHC Key Laboratory of Biosafety, National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China.
Zhenhai WangInstitute of Medical Sciences, General Hospital of Ningxia Medical University, Yinchuan, China.ORCID 0000-0002-3677-0985
Chinese Center For Disease Control and Prevention · CNXi'an Medical University · CNNingxia Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Japanese encephalitis virus (JEV), with neurotoxic and neuroinvasive properties, is the major cause of human viral encephalitis in Asia. Although Guillain-Barré syndrome caused by JEV infections is not frequent, a few cases have been reported in recent years. To date, no existing animal model for JEV-induced peripheral nerve injury (PNI) has been established, and thus the pathogenic mechanism is not clarified. Therefore, an animal model is urgently required to clarify the correlation between JEV infection and PNI. In the present study, we used JEV GIb strain of NX1889 to establish a mouse model of JEV infection. The general neurological signs emerged on day 3 of modeling. The motor function continued to deteriorate, reaching a maximum at 8 to 13 days postinfection (dpi) and gradually recovered after 16 dpi. The injuries of 10

Indexed as

Disease Models, AnimalEncephalitis, JapaneseEncephalitis Virus, JapanesePeripheral Nerve InjuriesAnimalsDemyelinating DiseasesHumansMiceMice, Inbred C57BLaxonC57BL/6 mouseJEVmyelin sheathPNIsciatic nerves

Identifiers

PMID37071015
PMCPMC10231255
OpenAlexW4366236809

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.