Evidence map›Paper›PMID 37070064›Full record

ArticleMovement disorders clinical practice2023

Reading Alterations in Parkinson's Disease Indicate Worse Cognitive Status.

Panagiota Tsitsi, Mattias Nilsson, Gustaf Öqvist Seimyr, Olof Larsson, Per Svenningsson, Ioanna Markaki

Open access · hybridAbstract read
In one paragraph

Article in Movement disorders clinical practice, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 2 pooled it
0.9field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 2 syntheses or guidelines pooled it, 7 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Review
  5. Pupil light reflex dynamics in Parkinson's disease.Frontiers in integrative neuroscience · 2023
    Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Panagiota TsitsiDepartment of Clinical Neuroscience Neuro, Karolinska Institutet Stockholm Sweden.ORCID https://orcid.org/0000-0003-3790-0398
Mattias NilssonDepartment of Clinical Neuroscience Eye and Vision, Karolinska Institutet Stockholm Sweden.
Gustaf Öqvist SeimyrDepartment of Clinical Neuroscience Eye and Vision, Karolinska Institutet Stockholm Sweden.
Olof LarssonDivision of Aging Research Center Karolinska Institutet Stockholm Sweden.
Per SvenningssonDepartment of Clinical Neuroscience Neuro, Karolinska Institutet Stockholm Sweden.ORCID https://orcid.org/0000-0001-6727-3802
Ioanna MarkakiDepartment of Clinical Neuroscience Neuro, Karolinska Institutet Stockholm Sweden.ORCID https://orcid.org/0000-0003-3328-5746
Karolinska Institutet · SEKarolinska University Hospital · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Reading difficulties are commonly reported in Parkinson's disease (PD). So far, only a few studies have assessed reading in PD, most of them confirming a different pattern in patients compared with healthy populations. Impaired oculomotor control is an early feature of PD. Cognitive deficits, on the other hand, may appear early, but they are most prominent at later stages. Although these two factors are thought to be responsible for the alterations in reading performance, it is unclear how each factor contributes to them. Objectives: To evaluate eye movements during reading in PD and healthy controls (HCs). Methods: Data from 42 HCs (36% men) and 48 patients with PD (67% men) at Hoehn and Yahr stages ≤3 were analyzed. PD participants were further divided into 2 groups based on their Montreal Cognitive Assessment (MoCA) score using a cutoff of ≥26. Eye movements were recorded with Tobii Pro Spectrum, a screen-based eye tracker with a sampling rate of 1200 Hz. Results: PD participants performed fewer fixations per second ( Conclusion: Changes in the reading pattern of PD patients are probably attributed to cognitive rather than pure oculomotor alterations.

Indexed as

CognitionEye‐movementsFixation durationParkinson's DiseaseReading

Identifiers

PMID37070064
PMCPMC10105091
OpenAlexW4317734003

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.