Evidence map›Paper›PMID 37069944›Full record

ArticleClinical ophthalmology (Auckland, N.Z.)2023

Novel Technique to Improve the Efficacy of Corneal Cross Linking in Cases of Post LASIK Ectasia.

Mohamed Omar Yousif, Rania Serag Elkitkat, Noha Abdelsadek Alaarag

Open access · goldAbstract read
In one paragraph

Article in Clinical ophthalmology (Auckland, N.Z.), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.9field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Mohamed Omar YousifOphthalmology Department, Faculty of Medicine, Ain Shams University, Cairo, Egypt.
Rania Serag ElkitkatOphthalmology Department, Faculty of Medicine, Ain Shams University, Cairo, Egypt.ORCID 0000-0001-7808-6658
Noha Abdelsadek AlaaragOphthalmology Department, Faculty of Medicine, Ain Shams University, Cairo, Egypt.
Ain Shams University · EG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: The aim of the present study was to validate the use of a novel technique that can improve the efficacy of corneal cross-linking (CXL) in cases with post LASIK ectasia. Methods: This is a retrospective, comparative study that was conducted on patients who sought medical advice at Ain Shams University Hospitals and Maadi Eye Subspeciality Center, Cairo, Egypt. It included two groups of patients with post LASIK ectasia. Group 1 included patients who performed our proposed protocol (topo-guided PRK, followed by customized phototherapeutic keratectomy "PTK" to transmit the laser treatment to the corneal stroma, then CXL). For group 2, accelerated CXL was performed. Subjective refraction and relevant topographic/tomographic parameters (Sirius topographer) compared between the two groups. Recorded follow-ups included the 2 to 3-month follow-up visit and the last visit (mean ± SD of 17.2 months ± 10.2). Results: Patients of group 1 (22 eyes of 22 patients) experienced significant improvements in most of the evaluated parameters at the 2- to 3-month follow-up visit and showed stability of the ectatic condition at the last follow-up visit, whereas patients of group 2 (10 eyes of 10 patients) showed stability of their ectatic condition at the 2- to 3-month follow-up visit, and one patient developed ectasia progression at the last follow-up visit. Conclusion: The present study validates the use of our novel protocol in cases having post LASIK ectasia with proven efficacy, safety, and stability, providing regularization for the corneal surface while simultaneously avoiding the unnecessary loss of cross-linking effect within the LASIK flap that no longer shares in the corneal biomechanical strength.

Indexed as

corneal cross-linkingnovel technique post LASIK ectasiapost LASIK ectasiapost LASIK ectasia managementstrengthening cross-linking efficacy

Identifiers

PMID37069944
PMCPMC10105569
OpenAlexW4364368429

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.