Evidence map›Paper›PMID 37069881›Full record

ReviewCureus2023

A Systematic Review of the Usage of Rotigotine During Early and Advanced Stage Parkinson's.

Avanthika Rajendran, Akshay J Reddy, Karol Bisaga, Dillon A Sommer, Neha Prakash, Vivek T Pokala, Zeyu Yu, Mark Bachir, Neel Nawathey, Telak Brahmbhatt and 1 more

Open access · diamondAbstract readReview
In one paragraph

Review in Cureus, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 1 country.

Avanthika RajendranNeuroscience, Reed College, Portland, USA.
Akshay J ReddyMedicine, California University of Science and Medicine, Colton, USA.
Karol BisagaMedicine, Midwestern University Chicago College of Osteopathic Medicine, Chicago, USA.
Dillon A SommerMedicine, California University of Science and Medicine, Colton, USA.
Neha PrakashMedicine, A.T. Still University, Osteopathic Medical School, Mesa, USA.
Vivek T PokalaHealth Sciences, California Northstate University, Rancho Cordova, USA.
Zeyu YuHealth Sciences, California Northstate University, Rancho Cordova, USA.
Mark BachirHealth Sciences, California Northstate University, Rancho Cordova, USA.
Neel NawatheyHealth Sciences, California Northstate University, Rancho Cordova, USA.
Telak BrahmbhattHealth Sciences, California Northstate University, Rancho Cordova, USA.
Rakesh PatelInternal Medicine, East Tennessee State University Quillen College of Medicine, Johnson City, USA.
Midwestern University · USGeneral Tire (United States) · USA.T. Still University · USEast Tennessee State University · USReed College · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Parkinson's disease (PD) is a prevalent neurodegenerative disorder that occurs in old age due to a decrease in dopamine, which causes nerve cell destruction. This disease is difficult to diagnose since its symptoms are similar to those of the aging process. Those with PD have impaired motor control and function, dyskinesia, and tremors. To treat PD, drugs that enhance the amount of dopamine given to the brain are administered to alleviate symptoms. This inquiry examines the prescription of rotigotine to achieve this objective. The primary objective of this review is to examine the usage of rotigotine in both the late and early stages of PD. The statistical model utilized in the review found that there was not a significant difference in the dosage of rotigotine prescribed to late and early-stage PD patients, however, there were some confounding variables that may have skewed this result; therefore, further research is necessary to validate or nullify this hypothesis.

Indexed as

levodopamotor delaymotor functionparkinson's diseaserotigotine

Identifiers

PMID37069881
PMCPMC10105263
OpenAlexW4327605600

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.