ArticleJournal of Korean medical science2023
The Epidemiological and Clinical Characteristics of the Largest Outbreak of Enterohemorrhagic
Article in Journal of Korean medical science, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed.
- Substrate secretion by different EHEC secretion systems during their interaction with epithelial cells.Virulence · 2026Article
- Genomic Insights into Ciprofloxacin-Resistant EnteropathogenicAntibiotics (Basel, Switzerland) · 2026Article
- Visual Screening of Genetic Polymorphisms inSensors (Basel, Switzerland) · 2026Article
- Evaluation of Single and Multi-Strain Probiotics with Gentamicin AgainstMicroorganisms · 2025Article
- Seasonal Analysis of PathogenicFood science & nutrition · 2025Article
- Article
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Authors and funding
8 authors.
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Abstract
backgroundThe largest outbreak of enterohemorrhagic
methodsEpidemiological investigation was performed on all 184 children and 19 workers at the preschool using a standard questionnaire to assess symptoms, food intake, attendance, and special activity history. Pulsed-field gel electrophoresis analysis of confirmed cases was performed to determine genetic relevance.
resultsDuring this outbreak, 103 children were affected, whereas only one infection was identified in adults. Of the 103 pediatric patients, 85 had symptoms (82.5%), including diarrhea, abdominal pain, bloody stool, fever, and vomiting. Thirty-two patients (31.1%) were hospitalized, 15 (14.6%) were diagnosed with hemolytic uremic syndrome, and 4 (3.9%) received dialysis treatment. Pulsed-field gel electrophoresis analysis identified 4 genotypes with high genetic relevance (92.3%). Epidemiological investigation revealed that this outbreak might have occurred from ingesting foods stored in a refrigerator with a constant temperature above 10°C, which was conducive to bacterial growth. Despite several measures after outbreak recognition, new infections continued to appear. Therefore, the preschool was forced to close on June 19 to prevent further person-to-person transmission.
conclusionOur findings from the response to the largest outbreak will help prepare countermeasures against future EHEC outbreak.
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