Evidence map›Paper›PMID 37069644›Full record

ArticleGenome biology2023

JBrowse 2: a modular genome browser with views of synteny and structural variation.

Colin Diesh, Garrett J Stevens, Peter Xie, Teresa De Jesus Martinez, Elliot A Hershberg, Angel Leung, Emma Guo, Shihab Dider, Junjun Zhang, Caroline Bridge and 10 more

Abstract read
In one paragraph

Article in Genome biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 550 papers.

0numbers the graph read from it
0cells of the map it votes in
550citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

550 citing papers in PubMed.

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  13. Programmed DNA elimination was present in the last common ancestor ofbioRxiv : the preprint server for biology · 2026
    Article
  14. Article
  15. Geranium: Multimodal Retrieval of Genomics Data Visualizations.IEEE transactions on visualization and computer graphics · 2026
    Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article

490 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors.

Colin DieshDepartment of Bioengineering, Stanley Hall, University of California, Berkeley, CA, 94720, USA.
Garrett J StevensDepartment of Bioengineering, Stanley Hall, University of California, Berkeley, CA, 94720, USA.
Peter XieDepartment of Bioengineering, Stanley Hall, University of California, Berkeley, CA, 94720, USA.
Teresa De Jesus MartinezDepartment of Bioengineering, Stanley Hall, University of California, Berkeley, CA, 94720, USA.
Elliot A HershbergDepartment of Bioengineering, Stanley Hall, University of California, Berkeley, CA, 94720, USA.
Angel LeungDepartment of Bioengineering, Stanley Hall, University of California, Berkeley, CA, 94720, USA.
Emma GuoDepartment of Bioengineering, Stanley Hall, University of California, Berkeley, CA, 94720, USA.
Shihab DiderDepartment of Bioengineering, Stanley Hall, University of California, Berkeley, CA, 94720, USA.
Junjun ZhangAdaptive Oncology, Ontario Institute for Cancer Research, MaRS Centre, 661 University Avenue, Suite 510, Toronto, ON, M5G 0A3, Canada.
Caroline BridgeAdaptive Oncology, Ontario Institute for Cancer Research, MaRS Centre, 661 University Avenue, Suite 510, Toronto, ON, M5G 0A3, Canada.
Gregory HogueAdaptive Oncology, Ontario Institute for Cancer Research, MaRS Centre, 661 University Avenue, Suite 510, Toronto, ON, M5G 0A3, Canada.
Andrew DuncanAdaptive Oncology, Ontario Institute for Cancer Research, MaRS Centre, 661 University Avenue, Suite 510, Toronto, ON, M5G 0A3, Canada.
Matthew MorganCenter for Applied Systems and Software, 224 Milne Computer Center, 1800 SW Campus Way, Oregon State University, Corvallis, OR, 97331, USA.
Tia FloresCenter for Applied Systems and Software, 224 Milne Computer Center, 1800 SW Campus Way, Oregon State University, Corvallis, OR, 97331, USA.
Benjamin N BimberOregon National Primate Research Center, Oregon Health and Science University, Beaverton, OR, 97006, USA.
Robin HawAdaptive Oncology, Ontario Institute for Cancer Research, MaRS Centre, 661 University Avenue, Suite 510, Toronto, ON, M5G 0A3, Canada.
Scott CainAdaptive Oncology, Ontario Institute for Cancer Research, MaRS Centre, 661 University Avenue, Suite 510, Toronto, ON, M5G 0A3, Canada.
Robert M BuelsDepartment of Bioengineering, Stanley Hall, University of California, Berkeley, CA, 94720, USA.
Lincoln D SteinAdaptive Oncology, Ontario Institute for Cancer Research, MaRS Centre, 661 University Avenue, Suite 510, Toronto, ON, M5G 0A3, Canada.
Ian H HolmesDepartment of Bioengineering, Stanley Hall, University of California, Berkeley, CA, 94720, USA. ihh@berkeley.edu.ORCID 0000-0001-7639-5369

Funding

Upgrade of confocal microscopy at the Oregon National Primate Research CenterP51OD011092 · OD · OREGON HEALTH & SCIENCE UNIVERSITY · PI Bonnie J. Nagel · 2012 to 2026
$203.9M
Web-based visualization of coronavirus genomes and proteinsR01HG004483 · NHGRI · UNIVERSITY OF CALIFORNIA BERKELEY · PI Ian H Holmes · 2007 to 2026
$9.3M
Novel Web-based Tools for Collaborative Community-Driven Genome Feature AnnotatioR01GM080203 · NIGMS · UNIVERSITY OF CALIFORNIA BERKELEY · PI Ian H Holmes · 2007 to 2026
$8.5M
Genomic Sequencing to Establish a Macaque Genotype and Phenotype Research ResourceR24OD021324 · OD · OREGON HEALTH & SCIENCE UNIVERSITY · PI BIMBER, BENJAMIN, WALL, JEFFREY D · 2016 to 2023
$7.7M
Developing the JBrowse Genome Browser to Visualize Structural Variants and Cancer Genomics DataU24CA220441 · NCI · UNIVERSITY OF CALIFORNIA BERKELEY · PI HOLMES, IAN H, STEIN, LINCOLN D. · 2017 to 2020
$2.7M
NCI NIH HHS U24 CA220441NHGRI NIH HHS R01 HG004483NIGMS NIH HHS R01 GM080203NIH HHS P51 OD011092NIH HHS R24 OD021324
6 · The paper itself

Abstract

We present JBrowse 2, a general-purpose genome annotation browser offering enhanced visualization of complex structural variation and evolutionary relationships. It retains core features of JBrowse while adding new views for synteny, dotplots, breakpoints, gene fusions, and whole-genome overviews. It allows users to share sessions, open multiple genomes, and navigate between views. It can be embedded in a web page, used as a standalone application, or run from Jupyter notebooks or R sessions. These improvements are enabled by a ground-up redesign using modern web technology. We describe application functionality, use cases, performance benchmarks, and implementation notes for web administrators and developers.

Indexed as

GenomicsSoftwareBiological EvolutionGenomeInternetSyntenyWeb Browser

Identifiers

PMID37069644
PMCPMC10108523

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.