ArticleBMC psychiatry2023
Association of remnant cholesterol with depression among US adults.
Article in BMC psychiatry, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
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Who cites it
28 citing papers in PubMed, 37 citations in OpenAlex.
- Associations of Midlife Vascular Risk Factors With Late-Life Depressive Symptoms: Findings From the ARIC Study.Journal of the American Heart Association · 2026Article
- Association Between C-Reactive Protein-Triglyceride Glucose Index and Depressive Symptoms Among US Adults: A Nationally Representative Cross-Sectional Study From 2005 to 2023.Actas espanolas de psiquiatria · 2026Article
- The mediating role of remnant cholesterol in the association between obstructive sleep apnea and diabetes: insights from two independent datasets.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2026Article
- Article
- Association of Remnant Cholesterol With Self‑Reported Trouble Sleeping and Mediation by Depression.Brain and behavior · 2026Article
- Higher remnant cholesterol inflammatory index is associated with increased frailty risk in the UK Biobank.Frontiers in nutrition · 2026Article
- Predictive model of neurocognitive functioning after acute coronary syndrome. A machine learning approach.Journal of cardiovascular and thoracic research · 2025Article
- Association between dietary niacin intake and suicidal ideation: mediating role of C-reactive protein.BMC psychiatry · 2025Article
- Cholesterol's hidden impact: the nonlinear link between remnant cholesterol (RC) and phenotypic age acceleration (PhenoAgeAccel).Biogerontology · 2025Article
- Association of remnant cholesterol with depression, type 2 diabetes, and their coexistence.BMC psychiatry · 2025Article
- Predicting peripartum depression using elastic net regression and machine learning: the role of remnant cholesterol.BMC pregnancy and childbirth · 2025Article
- Remnant cholesterol inflammatory index and its association with all-cause and cause-specific mortality in middle-aged and elderly populations: evidence from US and Chinese national population surveys.Lipids in health and disease · 2025Article
- Effects of remnant cholesterol on adverse renal outcomes in lupus nephritis.Lipids in health and disease · 2025Observational
- Association Between Remnant Cholesterol and Endometriosis Findings from NHANES 1999-2006.International journal of women's health · 2025Article
- Red blood cell distribution width to albumin ratio is associated with increased depression: the mediating role of atherogenic index of plasma.Frontiers in psychiatry · 2025Article
- Association between remnant cholesterol and depression in middle-aged and older Chinese adults: a population-based cohort study.Frontiers in endocrinology · 2025Article
- Association between depressive status and mild cognitive impairment in middle-aged and elderly Chinese adults from CHARLS study.Frontiers in psychiatry · 2025Article
- Remnant cholesterol and suicide attempts in untreated first-episode major depressive disorder.Frontiers in psychiatry · 2025Article
- Association between depression and liver function biomarkers among US cancer survivors in NHANES 2005-2020.Scientific reports · 2024Article
- Association between cardiorenal syndrome and depressive symptoms among the US population: a mediation analysis via lipid indices.Lipids in health and disease · 2024Article
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundRemnant cholesterol is receiving increasing attention because of its association with various diseases. However, there have been no studies on remnant cholesterol levels and depression.
methodsA cross-sectional analysis was performed based on the National Health and Nutrition Examination Survey (NHANES) 2005-2016. Depression was assessed using a Patient Health Questionnaire (PHQ-9). Fasting remnant cholesterol was calculated as the total cholesterol minus high-density lipoprotein cholesterol (HDL-C) minus low-density lipoprotein cholesterol (LDL-C). Logistic regression analysis with sampling weights was used to examine the association between remnant cholesterol concentration and depression.
resultsAmong 8,263 adults enrolled in this study (weighted mean age, 45.65 years), 5.88% (weighted percentage) had depression. Compared to the participants without depression, those with depression had higher concentration of remnant cholesterol (weighted mean, 26.13 vs. 23.05, P < 0.001). There was a significant positive relationship between remnant cholesterol concentration and depression and multivariable-adjusted OR with 95% CI was 1.49 (1.02-2.17). Among the subgroup analyses, remnant cholesterol concentration was positively associated with depression among participants less than 60 years (OR, 1.62; 95% CI, 1.09-2.42), male (OR, 2.02; 95% CI, 1.01-4.05), BMI under 30 (OR, 1.83; 95% CI, 1.14-2.96), and those with diabetes (OR, 3.88; 95% CI, 1.43-10.49).
conclusionsRemnant cholesterol concentration positively correlated with depression, suggesting that a focus on remnant cholesterol may be useful in the study of depression.
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