Evidence map›Paper›PMID 37069579›Full record

ArticleVeterinary research2023

Epitope mapping of the monoclonal antibody IP5B11 used for detection of viral haemorrhagic septicaemia virus facilitated by genome sequencing of carpione novirhabdovirus.

Takafumi Ito, Tohru Mekata, Niels Jørgen Olesen, Niels Lorenzen

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Veterinary research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.6field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 3 countries.

Takafumi ItoPathology Division, Fisheries Research Agency, Fisheries Technology Institute, 422-1 Nakatsuhamaura, Minami-Ise, Mie, 516-0193, Japan. ito_takafumi99@fra.go.jp.ORCID http://orcid.org/0000-0001-6275-1131
Tohru MekataPathology Division, Fisheries Research Agency, Fisheries Technology Institute, 422-1 Nakatsuhamaura, Minami-Ise, Mie, 516-0193, Japan.
Niels Jørgen OlesenNational Institute for Aquatic Resources, Technical University of Denmark, Kemitorvet 202, 2800, Kgs Lyngby, Denmark.
Niels LorenzenNational Institute for Aquatic Resources, Technical University of Denmark, Kemitorvet 202, 2800, Kgs Lyngby, Denmark.
Technical University of Denmark · DKFisheries Agency · TWOkayama University of Science · JP

Funding

JSPS KAKENHI 20K06218The Independent Research Fund Denmark 9041-00227B
6 · The paper itself

Abstract

The monoclonal antibody (mAb) IP5B11, which is used worldwide for the diagnosis of viral haemorrhagic septicaemia (VHS) in fish, reacts with all genotypes of VHS virus (VHSV). The mAb exceptionally also reacts with the carpione rhabdovirus (CarRV). Following next generation genome sequencing of CarRV and N protein sequence alignment including five kinds of fish novirhabdoviruses, the epitope recognized by mAb IP5B11 was identified. Dot blot analysis confirmed the epitope of mAb IP5B11 to be associated with the region N219 to N233 of the N protein of VHSV. Phylogenetic analysis identified CarRV as a new member of the fish novirhabdoviruses.

Indexed as

Fish DiseasesNovirhabdovirusAnimalsAntibodies, MonoclonalEpitope MappingEpitopesFishesPhylogenyAntibodies, MonoclonalEpitopesCarpione rhabdovirusEpitope mappingmAb IP5B11VHSV

Identifiers

PMID37069579
PMCPMC10111850
OpenAlexW4366086363

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.