ArticleBMC geriatrics2023
Quantitative CT screening improved lumbar BMD evaluation in older patients compared to dual-energy X-ray absorptiometry.
Article in BMC geriatrics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 1 of them a synthesis that pooled it.
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Who cites it
27 citing papers in PubMed, 1 synthesis or guideline pooled it, 41 citations in OpenAlex.
- Deep Learning-Assisted Automated Diagnosis of Osteoporosis Based on Computed Tomography Scans: Systematic Review and Meta-Analysis.Journal of medical Internet research · 2025Pooled it
- Thoracolumbar vertebral bone quality (TLVBQ) score as a possible screening tool for osteoporosis in patients with severe degenerative lumbar scoliosis: a retrospective cohort study.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026Article
- Comparison of the value of VBQ scores for assessing abnormal bone mass based on DXA and QCT.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026Article
- Radiation dose has no significant impact on CT-based bone mineral density measurements in a large-animal model.Scientific reports · 2026Article
- Lateral lumbar interbody fusion with lateral plating: techniques, feasibility and efficacy.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026Article
- Predictive efficacy of phantom-less calibration of computed tomography for cage subsidence after anterior cervical discectomy and fusion.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026Article
- Prevalence and regional distribution of osteoporosis in adults aged 75 years and older: a quantitative computed tomography-based retrospective cross-sectional study.BMC geriatrics · 2026Article
- Opportunistic osteoporosis screening using multiphase abdominal CT: reliable proximal femur BMD assessment with AI-assisted segmentation.Frontiers in medicine · 2026Article
- Investigation of age- and sex-related changes in cancellous bone density in the human spine using CT.PloS one · 2026Article
- Concordance of the Fracture Risk Assessment Tool With and Without Bone Mineral Density and Its Role in Predicting Postoperative Proximal Junctional Kyphosis After Adult Spinal Deformity Surgery.Neurosurgery practice · 2025Article
- Application of virtual monochromatic images in bone mineral density measurements: a phantom study.Scientific reports · 2025Article
- Using Phantomless QCT for evaluating BMD evolution in maintenance hemodialysis patients.Scientific reports · 2025Article
- Criteria for osteoporosis diagnosis: a systematic review and meta-analysis of osteoporosis diagnostic studies with DXA and QCT.EClinicalMedicine · 2025Article
- Quantitative metrics of bone quality determined at the distal radius using photon-counting CT.Skeletal radiology · 2025Article
- Undetected low bone mineral density in patients undergoing lumbar fusion surgery-prevalence and risk factors.North American Spine Society journal · 2025Article
- Quantitative CT lumbar spine BMD cutpoint value for classifying osteoporosis among older Chinese men can be the same as that of older Chinese women, both much lower than the value for Caucasians.Skeletal radiology · 2025Review
- Periostin Splice Variant Expression in Human Osteoblasts from Osteoporotic Patients and Its Effects on Interleukin-6 and Osteoprotegerin.International journal of molecular sciences · 2025Article
- Effects of different combinations of noise index and preset adaptive statistical iterative reconstruction Veo on the accuracy and image quality of bone mineral density measurements using fast kilovolt-switching dual-energy computed tomography: a phantom study.Quantitative imaging in medicine and surgery · 2025Article
- Thoracic vertebral bone mineral density measured by quantitative computed tomography is associated with fracture risk in lung cancer screening populations: a prospective cohort study.Frontiers in endocrinology · 2025Article
- Quantitative computed tomography analysis of proximal femur bone mineral density and its relation to hip fracture risk.Quantitative imaging in medicine and surgery · 2024Article
Corrections and comments
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Authors and funding
8 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundRobust evidence on whether diagnostic discordance exists between lumbar osteoporosis detected by quantitative computed tomography (QCT) vs. dual-energy X-ray absorptiometry (DXA) is still lacking. In this study involving a relatively large prospective cohort of older men (aged > 60 years) and postmenopausal women, we assessed lumbar QCT-derived volumetric bone mineral density (vBMD) and DXA-derived area BMD and evaluated their predictive performance for prevalent vertebral fracture (VF).
methodsA total of 501 patients who underwent spinal surgery from September 2020 to September 2022 were enrolled. The criteria recommended by the American College of Radiology and the World Health Organization were used for lumbar osteoporosis diagnosis. The osteoporosis detection rates between QCT and DXA were compared. QCT-vBMD was plotted against the DXA T score, and the line of best fit was calculated based on linear regression. Multivariate logistic regression was used to analyze the associations between risk factors and VF. Receiver operating characteristic curve analysis was performed, and the corresponding area under the curve (AUC) was calculated.
resultsQCT screening showed that 60.7% of patients had osteoporosis, whereas DXA screening showed that 50.7% of patients had osteoporosis. Diagnoses were concordant for 325 (64.9%) patients. In all, 205 patients suffered a VF of at least one anatomic level. Of these, 84.4% (173/205) were diagnosed with osteoporosis by QCT, while only 73.2% (150/205) were diagnosed by DXA. Multivariate logistic regression showed that osteoporosis detected by QCT exhibited a stronger relationship with VF than that detected by DXA (unadjusted OR, 6.81 vs. 5.04; adjusted OR, 3.44 vs. 2.66). For discrimination between patients with and without VF, QCT-vBMD (AUC = 0.802) showed better performance than DXA T score (AUC = 0.76).
conclusionIn older patients undergoing spinal surgery, QCT-vBMD is more helpful than DXA in terms of osteoporosis detection rate and prediction of patients with prevalent VFs.
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