Evidence map›Paper›PMID 37069510›Full record

Trial reportBMC cancer2023

Symptom management care pathway adaptation process and specific adaptation decisions.

Emily Vettese, Farha Sherani, Allison A King, Lolie Yu, Catherine Aftandilian, Christina Baggott, Vibhuti Agarwal, Ramamoorthy Nagasubramanian, Kara M Kelly, David R Freyer and 10 more

Registry-linked trialOpen access · goldAbstract readClinical Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in BMC cancer, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04614662 (Symptom Screening Linked to Care Pathways for Children With Cancer), which is not on this map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
2.6field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04614662 nacompletednot on this map

Symptom Screening Linked to Care Pathways for Children With Cancer: a Cluster Randomized Trial

TypeinterventionalSponsorThe Hospital for Sick ChildrenRan2021 to 2023Enrolled445ConditionsPediatric Cancer, Quality of LifeArmsSPARK Symptom Screening Linked to Feedback to Providers
3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 9 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors at 15 institutions in 2 countries.

Emily VetteseProgram in Child Health Evaluative Sciences, Peter Gilgan Centre for Research and Learning, The Hospital for Sick Children, 686 Bay Street, Toronto, ON, M5G 0A4, Canada.
Farha SheraniDriscoll Children's Hospital, Cancer and Blood Disorders Center, 3533 S. Alameda Street, Corpus Christi, TX, 78411, US.
Allison A KingWashington University School of Medicine, 660 S Euclid Ave, St Louis, MO, 63110, US.
Lolie YuLouisiana State University Health Sciences Center/Children's Hospital, 200 Henry Clay Avenue, New Orleans, LA, 70118, USA.
Catherine AftandilianStanford University, 800 Welch Road, Palo Alto, CA, 94304, US.
Christina BaggottStanford University, 800 Welch Road, Palo Alto, CA, 94304, US.
Vibhuti AgarwalNemours Children's Hospital of The Nemours Foundation, 6535 Nemours Parkway, Orlando, FL, 32827, US.
Ramamoorthy NagasubramanianNemours Children's Hospital of The Nemours Foundation, 6535 Nemours Parkway, Orlando, FL, 32827, US.
Kara M KellyRoswell Park Comprehensive Cancer Center, University at Buffalo Jacobs School of Medicine and Biomedical Sciences, 665 Elm St., Buffalo, NY, 14203, US.
David R FreyerCancer and Blood Disease Institute, Children's Hospital Los Angeles, 4650 Sunset Blvd, Los Angeles, CA, 90027, US.
Etan OrgelCancer and Blood Disease Institute, Children's Hospital Los Angeles, 4650 Sunset Blvd, Los Angeles, CA, 90027, US.
Scott M BradfieldNemours Children's Health, 807 Children's Way, Jacksonville, FL, 32207, US.
Wade KyonoKapi'olani Medical Center for Women & Children, 1319 Punahou Street, Honolulu, Hawai'i, 96826, US.
Michael RothDivision of Pediatrics, University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd, Houston, TX, 77030, US.
Lisa M KlesgesDivision of Public Health Sciences, Washington University School of Medicine, 600 So Taylor Ave, St. Louis, MO, 63110, US.
Melissa BeaucheminColumbia University School of Nursing/Herbert Irving Cancer Center, 560 West 168th Street, New York, NY, 10032, USA.
Allison GrimesPediatric Hematology Oncology, University of Texas Health, The Science Center at San Antonio, 7703 Floyd Curl Drive, San Antonio, TX, 78229, US.
George TomlinsonDepartment of Medicine, Toronto General Hospital, 200 Elizabeth Street, Toronto, ON, M5G 2C4, Canada.
L Lee DupuisProgram in Child Health Evaluative Sciences, Peter Gilgan Centre for Research and Learning, The Hospital for Sick Children, 686 Bay Street, Toronto, ON, M5G 0A4, Canada.
Lillian SungProgram in Child Health Evaluative Sciences, Peter Gilgan Centre for Research and Learning, The Hospital for Sick Children, 686 Bay Street, Toronto, ON, M5G 0A4, Canada. lillian.sung@sickkids.ca.
Children's Hospital of Los Angeles · USNemours Children's Clinic · USStanford University · USWashington University in St. Louis · USColumbia University · USHospital for Sick Children · CAKapiolani Medical Center for Women and Children · USLouisiana State University Health Sciences Center New Orleans · USRoswell Park Comprehensive Cancer Center · USSickKids Foundation · CATexas A&M University · USThe University of Texas Health Science Center at San Antonio · USThe University of Texas MD Anderson Cancer Center · USToronto General Hospital · CAUniversity of Toronto · CA

Funding

Symptom Screening Linked to Care Pathways for Children with Cancer: a Cluster Randomized TrialR01CA251112 · NCI · HOSPITAL FOR SICK CHLDRN (TORONTO) · PI DUPUIS, LAURA LEE, GRIMES, ALLISON · 2020 to 2024
$2.3M
CIHR PJT 169165NCI NIH HHS R01 CA251112NIH HHS 1R01CA251112
6 · The paper itself

Abstract

backgroundThere is substantial heterogeneity in symptom management provided to pediatric patients with cancer. The primary objective was to describe the adaptation process and specific adaptation decisions related to symptom management care pathways based on clinical practice guidelines. The secondary objective evaluated if institutional factors were associated with adaptation decisions.

methodsFourteen previously developed symptom management care pathway templates were reviewed by an institutional adaptation team composed of two clinicians at each of 10 institutions. They worked through each statement for all care pathway templates sequentially. The institutional adaptation team made the decision to adopt, adapt or reject each statement, resulting in institution-specific symptom management care pathway drafts. Institutional adaption teams distributed the 14 care pathway drafts to their respective teams; their feedback led to care pathway modifications.

resultsInitial care pathway adaptation decision making was completed over a median of 4.2 (interquartile range 2.0-5.3) weeks per institution. Across all institutions and among 1350 statements, 551 (40.8%) were adopted, 657 (48.7%) were adapted, 86 (6.4%) were rejected and 56 (4.1%) were no longer applicable because of a previous decision. Most commonly, the reason for rejection was not agreeing with the statement (70/86, 81.4%). Institutional-level factors were not significantly associated with statement rejection.

conclusionsAcceptability of the 14 care pathways was evident by most statements being adopted or adapted. The adaptation process was accomplished over a relatively short timeframe. Future work should focus on evaluation of care pathway compliance and determination of the impact of care pathway-consistent care on patient outcomes.

trial registrationclinicaltrials.gov, NCT04614662. Registered 04/11/2020, https://clinicaltrials.gov/ct2/show/NCT04614662?term=NCT04614662&draw=2&rank=1 .

Indexed as

Critical PathwaysNeoplasmsChildHumansPalliative CareCare pathwayClinical practice guidelinesImplementationOncologyPediatricSupportive careSymptom management

Identifiers

PMID37069510
PMCPMC10108500
OpenAlexW4366179088

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.