Evidence map›Paper›PMID 37069476›Full record

ArticleAnnals of surgical oncology2023

Pancreatoduodenectomy Following Preoperative Biliary Drainage Using Endoscopic Ultrasound-Guided Choledochoduodenostomy Versus a Transpapillary Stent: A Multicenter Comparative Cohort Study of the ACHBT-FRENCH-SFED Intergroup.

Julien Janet, Jeremie Albouys, Bertrand Napoleon, Jeremie Jacques, Muriel Mathonnet, Julien Magne, Marie Fontaine, Charles de Ponthaud, Sylvaine Durand Fontanier, Sylvia S M Bardet and 13 more

3 registry-linked trialsAbstract readMulticenter Study
PubMed Publisher
In one paragraph

Article in Annals of surgical oncology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
6.2field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06375928 naunknown statusnot on this mapstarted 2024, after this paper: background citation

Endoscopic Ultrasound-Guided Biliary Drainage With Lumen-Apposing Stent vs Classical ERCP for First-line Therapy of Malignant Distal Biliary Obstruction in Resectable Disease: An Open-label, Multicenter Randomized Controlled Trial (CARPEDIEM-1 Trial)

TypeinterventionalSponsorHospital Universitari de BellvitgeRan2024 to 2026Enrolled44ConditionsMalignant Biliary Obstruction, Pancreatic Cancer Resectable, Biliary Tract NeoplasmsArmsEndoscopic biliary drainage, Self-expandable metallic stent (SEMS), Lumen-apposing metal stent (LAMS) and double-pigtail plastic stent (DPPS)
NCT06375954 nanot yet recruitingnot on this mapstarted 2024, after this paper: background citation

Endoscopic Ultrasound-Guided Biliary Drainage With Lumen-Apposing Stent vs Classical ERCP for First-line Therapy of Malignant Distal Biliary Obstruction in Borderline Disease: An Open-label, Multicenter Randomized Trial (CARPEDIEM-2 Trial)

TypeinterventionalSponsorHospital Universitari de BellvitgeRan2024 to 2027Enrolled96ConditionsMalignant Biliary Obstruction, Pancreatic Cancer, Biliary Tract NeoplasmsArmsEndoscopic biliary drainage, Self-expandable metallic stent (SEMS), Lumen-apposing metal stent (LAMS) and double-pigtail plastic stent (DPPS)
NCT06653192 nasuspendednot on this mapstarted 2025, after this paper: background citation

Endoscopic Ultrasound-Guided Biliary Drainage With Lumen-Apposing Stent vs Classical ERCP for First-line Therapy of Malignant Distal Biliary Obstruction: An Open-label, Multicenter Randomized Trial (CARPEDIEM Trial)

TypeinterventionalSponsorHospital Universitari de BellvitgeRan2025 to 2028Enrolled120ConditionsMalignant Biliary Obstruction, Pancreatic Cancer, Biliary Tract NeoplasmsArmsEndoscopic biliary drainage, Self-expandable metallic stent (SEMS), Lumen-apposing metal stent (LAMS) and double-pigtail plastic stent (DPPS)
3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 27 citations in OpenAlex.

  1. Trial
  2. Article
  3. Review
  4. Review
  5. Article
  6. Review
  7. Article
  8. Article
  9. Review
  10. Review
  11. Review
  12. Article
  13. Article
  14. Article
  15. Review
  16. Review
  17. Review
  18. Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

23 authors at 10 institutions in 1 country.

Julien JanetDigestive Surgery Department, Dupuytren Limoges University Hospital, Limoges, France.
Jeremie AlbouysHepato-Gastroenterology Department, CHU Dupuytren, Limoges, France.
Bertrand NapoleonGastroenterology Department, Hôpital Privé Jean Mermoz, Ramsay Générale de Santé, Lyon, France.
Jeremie JacquesHepato-Gastroenterology Department, CHU Dupuytren, Limoges, France.
Muriel MathonnetDigestive Surgery Department, Dupuytren Limoges University Hospital, Limoges, France.
Julien MagneCEBIMER, University of Limoges, Limoges, France.
Marie FontaineGastroenterology Department, Hôpital Privé Jean Mermoz, Ramsay Générale de Santé, Lyon, France.
Charles de PonthaudDepartment of HPB and Endocrine Surgery, Hôpital la pitié salpêtrière, APHP, Paris, France.
Sylvaine Durand FontanierDigestive Surgery Department, Dupuytren Limoges University Hospital, Limoges, France.
Sylvia S M BardetCNRS, XLIM, UMR 7252, University of Limoges, Limoges, France.
Raphael BourdariatDigestive Surgery Department, Hôpital Privé Jean Mermoz, Ramsay Générale de Santé, Lyon, France.
Laurent SulpiceDepartment of Digestive Surgery, CHU de Rennes, Rennes, France.
Mickael LesurtelDepartment of HPB Surgery, Beaujon Hospital, APHP, Clichy, France.
Romain LegrosHepato-Gastroenterology Department, CHU Dupuytren, Limoges, France.
Stephanie TruantDepatment of Digestive Surgery and Transplantation, Hôpital Huriez - CHRU de Lille, Lille, France.
Fabien RobinDepartment of Digestive Surgery, CHU de Rennes, Rennes, France.
Frédéric PratDepartment of Endoscopy, Beaujon Hospital, APHP, Clichy, France.
Maxime PalazzoEndoscopy Unit, Hôpital Européen, Marseille, France.
Lilian SchwarzDigestive Surgery Department, CHU de Rouen, Rouen, France.
Emmanuel BucDigestive Surgery Department, CHU de Clermont, Ferrand, France.
Alain SauvanetDepartment of HPB Surgery, Beaujon Hospital, APHP, Clichy, France.
Sebastien GaujouxDepartment of HPB and Endocrine Surgery, Hôpital la pitié salpêtrière, APHP, Paris, France.
Abdelkader TaibiDigestive Surgery Department, Dupuytren Limoges University Hospital, Limoges, France. abdelkader.taibi@chu-limoges.fr.ORCID http://orcid.org/0000-0002-1036-6474
Centre National de la Recherche Scientifique · FRHôpital Beaujon · FRHôpital Dupuytren · FRHôpital Privé Jean Mermo · FRCentre Hospitalier Universitaire de Rennes · FRSorbonne Université · FRCentre Hospitalier Universitaire de Lille · FRCentre Hospitalier Universitaire de Rouen · FRHôpital Européen · FRUniversité de Limoges · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIt is unclear whether preoperative biliary drainage (PBD) by endoscopic retrograde cholangiopancreatography (ERCP) is equivalent to electrocautery-enhanced lumen-apposing metal stent (ECE-LAMS) before pancreatoduodenectomy (PD).

methodsPatients who underwent PBD for distal malignant biliary obstruction (DMBO) followed by PD were retrospectively included in nine expert centers between 2015 and 2022. ERCP or endoscopic ultrasound-guided choledochoduodenostomy with ECE-LAMS were performed. In intent-to-treat analysis, patients drained with ECE-LAMS were considered the study group (first-LAMS group) and those drained with conventional transpapillary stent the control group (first-cannulation group). The rates of technical success, clinical success, drainage-related complications, surgical complications, and oncological outcomes were analyzed.

resultsAmong 156 patients, 128 underwent ERCP and 28 ECE-LAMS in first intent. The technical and clinical success rates were 83.5% and 70.2% in the first-cannulation group versus 100% and 89.3% in the first-LAMS group (p = 0.02 and p = 0.05, respectively). The overall complication rate over the entire patient journey was 93.7% in first-cannulation group versus 92.0% in first-LAMS group (p = 0.04). The overall endoscopic complication rate was 30.5% in first-cannulation group versus 17.9% in first-LAMS group (p = 0.25). The overall complication rate after PD was higher in the first-cannulation group than in the first-LAMS group (92.2% versus 75.0%, p = 0.016). Overall survival and progression-free survival did not differ between the groups.

conclusionsPBD with ECE-LAMS is easier to deploy and more efficient than ERCP in patients with DMBO. It is associated with less surgical complications after pancreatoduodenectomy without compromising the oncological outcome.

Indexed as

CholedochostomyCholestasisCholangiopancreatography, Endoscopic RetrogradeCohort StudiesDrainageEndosonographyHumansPancreaticoduodenectomyRetrospective StudiesStentsUltrasonography, Interventional

Identifiers

PMID37069476
OpenAlexW4366140970

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.