Evidence map›Paper›PMID 37069473›Full record

ArticleReproductive sciences (Thousand Oaks, Calif.)2023

Total Sialic Acid, Antioxidant Enzyme Activities, Trace Elements, and Vitamin Status Before and After Surgery in Women with Uterine Myoma and Endometrial Cancer.

Fazilet Gök, Suat Ekin, Erbil Karaman, Remzi Erten, Damla Yıldız, Ahmet Bakır

Abstract read
PubMed Publisher
In one paragraph

Article in Reproductive sciences (Thousand Oaks, Calif.), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 6 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Fazilet GökDepartment of Chemistry, Division of Biochemistry, Institute of Natural and Applied Sciences, Van Yuzuncu Yil University, Van, Turkey.ORCID 0000-0001-6328-6905
Suat EkinDepartment of Chemistry, Division of Biochemistry, Science Faculty, Van Yuzuncu Yil University, Van, Turkey. suatekin@hotmail.com.ORCID 0000-0002-6502-5028
Erbil KaramanDepartment of Gynecology and Obstetrics, Division of Gynecological Oncology, Van Yuzuncu Yil University, Van, Turkey.ORCID 0000-0003-1058-2748
Remzi ErtenDepartment of Medical Pathology, Van Yuzuncu Yil University, Van, Turkey.ORCID 0000-0001-7775-5792
Damla YıldızDepartment of Chemistry, Division of Biochemistry, Institute of Natural and Applied Sciences, Van Yuzuncu Yil University, Van, Turkey.ORCID 0000-0002-9489-3860
Ahmet BakırDepartment of Chemistry, Division of Biochemistry, Institute of Natural and Applied Sciences, Van Yuzuncu Yil University, Van, Turkey.ORCID 0000-0003-0797-285X
Van Yüzüncü Yıl Üniversitesi · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The objective of present study was to examine endometrial tissue Be, As, Cr, Mo, Sr, Ti, Tl, Cu, Co, Se, Zn, Mn, Fe, Cd, Pb, Mg, P, erythrocytes CAT, SOD, GSH-Px, GSH, MDA, serum retinol, cholecalciferol, phylloquinone, TSA, LSA, TOS, and TAS status and to evaluate the relationships between the variables. The study had 110 participants; of these, 50 were women with uterine myoma (UM), 10 were women with endometrial cancer (EC), and 50 were healthy female subjects. In the study, vitamin analyses by HPLC and element analyses were determined using ICP-OES method. It was observed that EC group was significantly lower than healthy group in terms of levels of cholecalciferol (p < 0.05), phylloquinone (p < 0.01), GSH (p < 0.05), Fe (p < 0.05), and had a significant rise in Mg/Fe (p < 0.01) and Zn/Fe (p < 0.05) in preoperative period. UM group had significantly lower retinol (p < 0.05), phylloquinone (p < 0.001), GSH-Px (p < 0.01), GSH (p < 0.01), Cr (p < 0.01), Cu (p < 0.05), Mg (p < 0.01), and Zn (p < 0.01) levels than control group in preoperative period and significantly higher levels of MDA (p < 0.01), TSA (p < 0.01), and LSA (p < 0.01) than control group. It was found that significant associations were observed between Cu-CA 15-3 (r = 0.558, p = 0.016), Mn-CA 15-3 (r = 0.511, p = 0.030), P-CA 15-3(r =  - 0.502, p = 0.034) and with UM, also between GSH-CA-125 (r =  - 0.825, p = 0.022) and with EC group. The results of correlation analysis observed that concentrations of Cu, Mn, P, and GSH together with CA 15-3 and CA-125 levels might be important for monitoring patients with UM and EC before surgery.

Indexed as

Endometrial NeoplasmsMyomaTrace ElementsAntioxidantsCholecalciferolFemaleHumansN-Acetylneuraminic AcidVitamin AVitamin K 1VitaminsAntioxidantsCholecalciferolN-Acetylneuraminic AcidTrace ElementsVitamin AVitamin K 1VitaminsAntioxidantEndometrial cancerTotal sialic acidTrace elementUterine myomaVitamin

Identifiers

PMID37069473
OpenAlexW4366145074

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.