Evidence map›Paper›PMID 37069415›Full record

ArticleNeurochemical research2023

Differential Effects of Chronic Ethanol Use on Mouse Neuronal and Astroglial Metabolic Activity.

Unis Ahmad Bhat, Sreemantula Arun Kumar, Sumana Chakravarty, Anant Bahadur Patel, Arvind Kumar

Abstract read
PubMed Publisher
In one paragraph

Article in Neurochemical research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Trial
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Unis Ahmad BhatEpigenetics and Neuropsychiatric Disorders Laboratory, CSIR-Centre for Cellular and Molecular Biology (CCMB), Uppal Road, Habsiguda, Hyderabad, Telangana State (TS), 500007, India.
Sreemantula Arun KumarApplied Biology, CSIR-Indian Institute of Chemical Technology, Hyderabad, Telangana, India.
Sumana ChakravartyApplied Biology, CSIR-Indian Institute of Chemical Technology, Hyderabad, Telangana, India.
Anant Bahadur PatelEpigenetics and Neuropsychiatric Disorders Laboratory, CSIR-Centre for Cellular and Molecular Biology (CCMB), Uppal Road, Habsiguda, Hyderabad, Telangana State (TS), 500007, India. abpatel@ccmb.res.in.ORCID http://orcid.org/0000-0002-9551-9395
Arvind KumarEpigenetics and Neuropsychiatric Disorders Laboratory, CSIR-Centre for Cellular and Molecular Biology (CCMB), Uppal Road, Habsiguda, Hyderabad, Telangana State (TS), 500007, India. akumar@ccmb.res.in.ORCID http://orcid.org/0000-0003-2879-3826
Centre for Cellular and Molecular Biology · INIndian Institute of Chemical Technology · IN

Funding

Department of Biotechnology, Ministry of Science and Technology, India BT/PR27426/MED/122/140/2018
6 · The paper itself

Abstract

Chronic alcohol use disorder, a major risk factor for the development of neuropsychiatric disorders including addiction to other substances, is associated with several neuropathology including perturbed neuronal and glial activities in the brain. It affects carbon metabolism in specific brain regions, and perturbs neuro-metabolite homeostasis in neuronal and glial cells. Alcohol induced changes in the brain neurochemical profile accompany the negative emotional state associated with dysregulated reward and sensitized stress response to withdrawal. However, the underlying alterations in neuro-astroglial activities and neurochemical dysregulations in brain regions after chronic alcohol use are poorly understood. This study evaluates the impact of chronic ethanol use on the regional neuro-astroglial metabolic activity using

Indexed as

AstrocytesGlucoseAcetatesAnimalsBrainEthanolMagnetic Resonance SpectroscopyMiceAcetatesEthanolGlucose13C NMR spectroscopyAlcohol abuseAstrocytesBrain metabolismGABAGlutamateMonocarboxylic acid transportersNeurons

Identifiers

PMID37069415
OpenAlexW4366142410

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.