Evidence map›Paper›PMID 37069363›Full record

ArticleNature medicine2023

Incident type 2 diabetes attributable to suboptimal diet in 184 countries.

Meghan O'Hearn, Laura Lara-Castor, Frederick Cudhea, Victoria Miller, Julia Reedy, Peilin Shi, Jianyi Zhang, John B Wong, Christina D Economos, Renata Micha and 2 more

Registry-linked trialOpen access · hybridAbstract read
In one paragraph

Article in Nature medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06242535 (Pilot Study of GLY-LOW Supplementation in Postmenopausal Women With Obesity), which is not on this map. Cited by 92 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
92citing papers in PubMed, 2 pooled it
52.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06242535 early_phase1completednot on this map

Pilot Study of GLY-LOW Supplementation in Postmenopausal Women With Obesity

TypeinterventionalSponsorHoskinson Health and Wellness ClinicRan2023 to 2024Enrolled13ConditionsInsulin Resistance, Obesity, Cardiovascular Diseases, Cognitive ImpairmentArmsGLY-LOW
3 · Its place in the literature

Who cites it

92 citing papers in PubMed, 2 syntheses or guidelines pooled it, 171 citations in OpenAlex.

  1. Pooled it
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  19. Type 2 diabetes mellitus.Nature reviews. Disease primers · 2026
    Review
  20. Type 2 diabetes mellitus exacerbates vaginal group BbioRxiv : the preprint server for biology · 2026
    Article

32 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

12 authors at 20 institutions in 67 countries.

Meghan O'HearnFriedman School of Nutrition Science and Policy, Tufts University, Boston, MA, USA. meghan.o_hearn@tufts.edu.ORCID http://orcid.org/0000-0001-5712-3077
Laura Lara-CastorFriedman School of Nutrition Science and Policy, Tufts University, Boston, MA, USA.ORCID http://orcid.org/0000-0002-1750-5406
Frederick CudheaFriedman School of Nutrition Science and Policy, Tufts University, Boston, MA, USA.
Victoria MillerFriedman School of Nutrition Science and Policy, Tufts University, Boston, MA, USA.ORCID http://orcid.org/0000-0003-0509-1549
Julia ReedyFriedman School of Nutrition Science and Policy, Tufts University, Boston, MA, USA.
Peilin ShiFriedman School of Nutrition Science and Policy, Tufts University, Boston, MA, USA.
Jianyi ZhangFriedman School of Nutrition Science and Policy, Tufts University, Boston, MA, USA.
John B WongTufts University School of Medicine, Boston, MA, USA.ORCID http://orcid.org/0000-0003-4203-9010
Christina D EconomosFriedman School of Nutrition Science and Policy, Tufts University, Boston, MA, USA.
Renata MichaFriedman School of Nutrition Science and Policy, Tufts University, Boston, MA, USA.
Dariush MozaffarianFriedman School of Nutrition Science and Policy, Tufts University, Boston, MA, USA. dariush.mozaffarian@tufts.edu.ORCID http://orcid.org/0000-0001-7958-9492
Global Dietary Database
Tufts University · USIsfahan University of Medical Sciences · IRNational Institute of Nutrition · INNational Food Administration · SEStatistics Canada · CAInstituto Nacional de Salud Pública · MXUniversidade do Porto · PTCGIAR · FRNational Nutrition and Food Technology Research Institute · IRUniversity of North Carolina at Chapel Hill · US"Dunarea de Jos" University of Galati · ROGhent University Hospital · BEInstitute of Biomedical Sciences, Academia Sinica · TWIstituto Nazionale di Ricerca per gli Alimenti e la Nutrizione · ITIstituto Neurologico Mediterraneo · ITJehangir Hospital · INKenya Medical Research Institute · KEMinistry of Health · MYNational Center of Public Health and Analyses · BGNutrition Center of the Philippines · PH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The global burden of diet-attributable type 2 diabetes (T2D) is not well established. This risk assessment model estimated T2D incidence among adults attributable to direct and body weight-mediated effects of 11 dietary factors in 184 countries in 1990 and 2018. In 2018, suboptimal intake of these dietary factors was estimated to be attributable to 14.1 million (95% uncertainty interval (UI), 13.8-14.4 million) incident T2D cases, representing 70.3% (68.8-71.8%) of new cases globally. Largest T2D burdens were attributable to insufficient whole-grain intake (26.1% (25.0-27.1%)), excess refined rice and wheat intake (24.6% (22.3-27.2%)) and excess processed meat intake (20.3% (18.3-23.5%)). Across regions, highest proportional burdens were in central and eastern Europe and central Asia (85.6% (83.4-87.7%)) and Latin America and the Caribbean (81.8% (80.1-83.4%)); and lowest proportional burdens were in South Asia (55.4% (52.1-60.7%)). Proportions of diet-attributable T2D were generally larger in men than in women and were inversely correlated with age. Diet-attributable T2D was generally larger among urban versus rural residents and higher versus lower educated individuals, except in high-income countries, central and eastern Europe and central Asia, where burdens were larger in rural residents and in lower educated individuals. Compared with 1990, global diet-attributable T2D increased by 2.6 absolute percentage points (8.6 million more cases) in 2018, with variation in these trends by world region and dietary factor. These findings inform nutritional priorities and clinical and public health planning to improve dietary quality and reduce T2D globally.

Indexed as

Diabetes Mellitus, Type 2AdultBody WeightDietFemaleGlobal HealthHumansIncomeMaleRisk AssessmentRisk Factors

Identifiers

PMID37069363
PMCPMC10115653
OpenAlexW4366162936

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.