Evidence map›Paper›PMID 37069316›Full record

ArticleScientific reports2023

Acrylonitrile adducts: design, synthesis and biological evaluation as antimicrobial, haemolytic and thrombolytic agent.

Parineeta Das, Nirmala Devi, Nisha Gaur, Swagata Goswami, Dhiraj Dutta, Rama Dubey, Amrit Puzari

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Parineeta DasDepartment of Chemistry, National Institute of Technology Nagaland, Chumoukedima, Nagaland, 797103, India.
Nirmala DeviChulalongkorn University, Bangkok, 10330, Thailand.
Nisha GaurDefence Research Laboratory, Post Bag No. 2, Tezpur, Assam, 784001, India.
Swagata GoswamiDefence Research Laboratory, Post Bag No. 2, Tezpur, Assam, 784001, India.
Dhiraj DuttaDefence Research Laboratory, Post Bag No. 2, Tezpur, Assam, 784001, India.
Rama DubeyDefence Research Laboratory, Post Bag No. 2, Tezpur, Assam, 784001, India.
Amrit PuzariDepartment of Chemistry, National Institute of Technology Nagaland, Chumoukedima, Nagaland, 797103, India. amrit09us@yahoo.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this work, five acrylonitrile adducts were screened for antibacterial activity against Gram-positive Bacillus subtilis, Microbial Type Culture Collection and Gene Bank (MTCC 1305) and Gram-negative Escherichia coli (MTCC 443). Synthesis was followed by aza-Michael addition reaction, where the acrylonitrile accepts an electron pair from the respective amines and results in the formation of n-alkyliminobis-propionitrile and n-alkyliminopropionitrile under microwave irradiation. Characterization of the compounds were performed using Fourier Transform Infrared (FTIR), Proton Nuclear Magnetic Resonance (

Indexed as

AcrylonitrileAnti-Infective AgentsAnimalsAnti-Bacterial AgentsBacillus subtilisEscherichia coliFibrinolytic AgentsGram-Negative BacteriaMiceMicrobial Sensitivity TestsAcrylonitrileAnti-Bacterial AgentsAnti-Infective AgentsFibrinolytic Agents

Identifiers

PMID37069316
PMCPMC10110592

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.