Trial reportScientific reports2023
Effects of sleep fragmentation and partial sleep restriction on heart rate variability during night.
Trial report in Scientific reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
28 citing papers in PubMed.
- Stage-specific polysomnographic and MRI markers across phenoconversion in isolated REM sleep behavior disorder.Journal of neurology · 2026Observational
- Heart rate and vascular responses to spontaneous arousals following experimental sleep restriction.American journal of physiology. Heart and circulatory physiology · 2026Article
- Sleep Hygiene Improves Aerobic and Anaerobic Performance Independent of Cortisol Mediation in Female Collegiate Soccer Players.Journal of functional morphology and kinesiology · 2026Article
- Clinical Care Interaction and Patient Sleep in the Intensive Care Unit: A Secondary Data Analysis.Nursing in critical care · 2026Article
- Association of meeting the 24-hour movement guidelines with heart rate variability in adults.European journal of applied physiology · 2026Article
- Sleep stage classification from ECG using machine learning: Evaluating the impact of signal duration.Neurobiology of sleep and circadian rhythms · 2026Article
- Effects of Sleep Duration on Electroencephalographic and Autonomic Nervous System Responses to High-Intensity Exercise.Healthcare (Basel, Switzerland) · 2026Article
- Device-assessed sleep health among older patients with heart failure: a cross-sectional study using actigraphy.BMJ open · 2026Article
- Which psychosocial job demands matter most for parasympathetic heart rate variability? A dominance analysis study.Journal of occupational health · 2026Article
- Sleep structure and autonomic nervous system state during four months of isolation in a space analogue mission.Frontiers in human neuroscience · 2026Article
- The interaction between exercise and sleep with heart rate variability: cross-sectional study.European journal of applied physiology · 2026Article
- Interpreting heart rate variability in clinical context: a framework for understanding a multidimensional autonomic biomarker.Frontiers in cardiovascular medicine · 2026Review
- Association Between Sleep Duration and Angina Characteristics in United States Adults.American journal of medicine open · 2025Article
- Article
- Cross-Sectional Analysis of Sleep Quality and Vascular Health in Shift- and Day-Working Nurses.Clocks & sleep · 2025Article
- Individual training prescribed by heart rate variability, heart rate and well-being scores in experienced cyclists.Scientific reports · 2025Article
- The cardiovascular consequences of chronic sleep fragmentation: Evidence from experimental models of obstructive sleep apnea.Sleep medicine · 2025Article
- Effects of 24-h sleep deprivation on whole-body heat exchange in young men during exercise in the heat.European journal of applied physiology · 2025Article
- Actigraphy-based sleep disruption and diurnal biomarkers of autonomic function in paroxysmal atrial fibrillation.Sleep & breathing = Schlaf & Atmung · 2025Article
- Wearables in Chronomedicine and Interpretation of Circadian Health.Diagnostics (Basel, Switzerland) · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We developed a cross-over study design with two interventions in randomized order to compare the effects of sleep fragmentation and partial sleep restriction on cardiac autonomic tone. Twenty male subjects (40.6 ± 7.5 years old) underwent overnight polysomnography during 2 weeks, each week containing one undisturbed baseline night, one intervention night (either sleep restriction with 5 h of sleep or sleep fragmentation with awakening every hour) and two undisturbed recovery nights. Parameters of heart rate variability (HRV) were used to assess cardiac autonomic modulation during the nights. Sleep restriction showed significant higher heart rate (p = 0.018) and lower HRV-pNN50 (p = 0.012) during sleep stage N1 and lower HRV-SDNN (p = 0.009) during wakefulness compared to the respective baseline. For HR and SDNN there were recovery effects. There was no significant difference comparing fragmentation night and its baseline. Comparing both intervention nights, sleep restriction had lower HRV high frequency (HF) components in stage N1 (p = 0.018) and stage N2 (p = 0.012), lower HRV low frequency (LF) (p = 0.007) regarding the entire night and lower SDNN (p = 0.033) during WASO during sleep. Sleep restriction increases sympathetic tone and decreases vagal tone during night causing increased autonomic stress, while fragmented sleep does not affect cardiac autonomic parameters in our sample.
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