ArticleScientific reports2023
Disappearance, division, and route change of excitable reaction-diffusion waves in deformable membranes.
Article in Scientific reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed, 11 citations in OpenAlex.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
Abstract
Shapes of biomembrane in living cells are regulated by curvature-inducing proteins. However, the effects of membrane deformation on signal transductions such as chemical waves have not been researched adequately. Here, we report that membrane deformation can alter the propagation of excitable reaction-diffusion waves using state-of-the-art simulations. Reaction waves can induce large shape transformations, such as membrane budding and necking, that erase or divide the wave, depending on the curvature generated by the waves, feedback to the wave propagation, and the ratio of the reaction and deformation times. In genus-2 vesicles, wave division occurs at branching points and collided waves disappear together. We demonstrate that the occasional disappearance of the waves can alter the pathway of wave propagation. Our findings suggest that membrane deformation and reaction waves can together regulate signal transductions on biomembranes.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.