Evidence map›Paper›PMID 37069193›Full record

ArticleNPJ Parkinson's disease2023

Using a smartwatch and smartphone to assess early Parkinson's disease in the WATCH-PD study.

Jamie L Adams, Tairmae Kangarloo, Brian Tracey, Patricio O'Donnell, Dmitri Volfson, Robert D Latzman, Neta Zach, Robert Alexander, Peter Bergethon, Joshua Cosman and 14 more

Open access · goldAbstract read
In one paragraph

Article in NPJ Parkinson's disease, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 55 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
55citing papers in PubMed, 4 pooled it
15.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

55 citing papers in PubMed, 4 syntheses or guidelines pooled it, 87 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Article
  6. Article
  7. Article
  8. Observational
  9. Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. Review
  15. Review
  16. Article
  17. Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

24 authors at 20 institutions in 1 country.

Jamie L AdamsCenter for Health + Technology, University of Rochester Medical Center, Rochester, NY, USA. jamie_adams@urmc.rochester.edu.ORCID http://orcid.org/0000-0002-1170-6688
Tairmae KangarlooTakeda Pharmaceuticals, Cambridge, MA, USA.
Brian TraceyTakeda Pharmaceuticals, Cambridge, MA, USA.ORCID http://orcid.org/0000-0003-1526-6349
Patricio O'DonnellTakeda Pharmaceuticals, Cambridge, MA, USA.ORCID http://orcid.org/0000-0001-7788-624X
Dmitri VolfsonTakeda Pharmaceuticals, Cambridge, MA, USA.
Robert D LatzmanTakeda Pharmaceuticals, Cambridge, MA, USA.ORCID http://orcid.org/0000-0002-1175-8090
Neta ZachTakeda Pharmaceuticals, Cambridge, MA, USA.
Robert AlexanderTakeda Pharmaceuticals, Cambridge, MA, USA.
Peter BergethonInvariant Research Limited, Dover, MA, USA.
Joshua CosmanAbbVie Pharmaceuticals, North Chicago, IL, USA.
David AndersonClinical Ink, Horsham, PA, USA.
Allen BestClinical Ink, Horsham, PA, USA.ORCID http://orcid.org/0000-0001-9363-4173
Joan SeversonClinical Ink, Horsham, PA, USA.
Melissa A KostrzebskiCenter for Health + Technology, University of Rochester Medical Center, Rochester, NY, USA.
Peggy AuingerCenter for Health + Technology, University of Rochester Medical Center, Rochester, NY, USA.
Peter WilmotCenter for Health + Technology, University of Rochester Medical Center, Rochester, NY, USA.
Yvonne PohlsonCenter for Health + Technology, University of Rochester Medical Center, Rochester, NY, USA.
Emma WaddellCenter for Health + Technology, University of Rochester Medical Center, Rochester, NY, USA.ORCID http://orcid.org/0000-0002-8863-0335
Stella Jensen-RobertsCenter for Health + Technology, University of Rochester Medical Center, Rochester, NY, USA.
Yishu GongTakeda Pharmaceuticals, Cambridge, MA, USA.ORCID http://orcid.org/0000-0002-7777-6363
Krishna Praneeth KilambiDepartment of Radiology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.ORCID http://orcid.org/0000-0003-4848-2611
Teresa Ruiz HerreroBill and Melinda Gates Foundation, Seattle, WA, USA.
E Ray DorseyCenter for Health + Technology, University of Rochester Medical Center, Rochester, NY, USA.ORCID http://orcid.org/0000-0002-5140-1248
Parkinson Study Group Watch-PD Study Investigators and Collaborators
University of Rochester Medical Center · USTakeda (United States) · USBanner Health · USBiogen (United States) · USDigital Artefacts (United States) · USNorthwestern University · USOregon Health & Science University · USUniversity Hospitals of Cleveland · USUniversity of California, San Francisco · USUniversity of South Florida · USNew York University · USSentara Virginia Beach General Hospital · USBaylor College of Medicine · USCleveland Clinic · USCritical Path Institute · USUniversity of Cincinnati · USUniversity of Colorado Denver · USUniversity of Michigan · USVirginia Commonwealth University · USAbbVie (United States) · US

Funding

Oregon Clinical and Translational Research Institute - The National COVID Cohort Collaborative (N3C)UL1TR002369 · NCATS · OREGON HEALTH & SCIENCE UNIVERSITY · PI Cynthia D Morris, Christopher G. Slatore · 2017 to 2026
$78.4M
NCATS NIH HHS UL1 TR002369
6 · The paper itself

Abstract

Digital health technologies can provide continuous monitoring and objective, real-world measures of Parkinson's disease (PD), but have primarily been evaluated in small, single-site studies. In this 12-month, multicenter observational study, we evaluated whether a smartwatch and smartphone application could measure features of early PD. 82 individuals with early, untreated PD and 50 age-matched controls wore research-grade sensors, a smartwatch, and a smartphone while performing standardized assessments in the clinic. At home, participants wore the smartwatch for seven days after each clinic visit and completed motor, speech and cognitive tasks on the smartphone every other week. Features derived from the devices, particularly arm swing, the proportion of time with tremor, and finger tapping, differed significantly between individuals with early PD and age-matched controls and had variable correlation with traditional assessments. Longitudinal assessments will inform the value of these digital measures for use in future clinical trials.

Identifiers

PMID37069193
PMCPMC10108794
OpenAlexW4366086083

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.